...: Phosphorylations of the conserved serine cluster in the Drosophila E-Cadherin intracellular tail are quantitatively rather than site specifically required for its function in adherens junction formation. DE-Cadherin β-Catenin Shotgun Armadillo α-Catenin Adherens junctions Apical-basal polarity...

... of brain neuroblasts (NBs) in Drosophila utilize Phosphoinositide 3-kinase (PI3-kinase) and DE-cadherin to build adhesive contact for NB niche positioning. NBs remain within their native microenvironment when levels of PI3-kinase activity and DE-cadherin are elevated in NBs. This occurs through PI3-kinase...

... regulator of BCC migration. Tj has a multifaceted impact on the known core cascade that enables BCC motility, consisting of the Jak/Stat signaling pathway, the C/EBP factor Slow border cells (Slbo), and the downstream effector DE-cadherin (DEcad). The initiation of BCC migration coincides with a Slbo...

... junction in Drosophila L/R asymmetry. Here, we show that DE-Cadherin co-immunoprecipitates with MyoID and is required for MyoID L/R activity. We further demonstrate that MyoIC, a closely related unconventional type I myosin, can antagonize MyoID L/R activity by preventing its binding to adherens junction...

... the proteins involved remain largely unknown. Here, we show that Canoe (Cno), the Drosophila ortholog of AF-6, and the DE-cadherin Shotgun (Shg) are highly restricted to the interface between midline glia and commissural axons. cno mutant analysis, genetic interactions and co-immunoprecipitation assays unveil...

... pathway governing tracheal formation and cell adhesiveness. * Author for correspondence (e-mail: mlcbmc@cid.csic.es ) 7 6 2006 © 2006. 2006 Epithelial integrity Egfr Tracheal system ERK type MAPK pathway Mkp3 Cell adhesion DE-cadherin Cortical actin Drosophila...

... that gonad formation in Drosophila requires the homophilic cell-adhesion molecule Drosophila E-cadherin (DE-cadherin), and also Fear of Intimacy (FOI), which is required for stable accumulation of DE-cadherin protein in the gonad. Here, we present an in vivo structure-function analysis of FOI that strongly...

... classic cadherin, DE-cadherin, which is encoded by the shotgun ( shg ) gene. The visual system is derived from the optic placode which normally invaginates from the surface ectoderm of the embryo and gives rise to two separate structures, the larval eye (Bolwig’s organ) and the optic lobe. The optic...

... of gene transcription, DE-cadherin-based cell-cell adhesion and cell polarity underlie the effects of DRhoA N19 expression. Furthermore, we demonstrate that these changes in cell physiology have a differential effect on the epidermis that is dependent upon position in the dorsoventral axis. In the ventral...