... individual cells, changes in shape are driven by the cytoskeleton. Over the last decade, enormous progress has been made in deciphering which type of cell shape changes drive changes at the tissue scale ( Blanchard et al., 2009 ; Guirao et al., 2015 ; Herrera-Perez and Kasza, 2018 ). Cell shape changes...

..., reveal a role for the C. elegans actin-capping protein CAP-1 in regulation of actomyosin contractility to maintain reproductive tissue architecture and fertility. Actin dynamics Capping protein Cytoskeleton Actomyosin Contractility Caenorhabditis elegans Syncytial germline Formins Arp2...

... of nuclei in multinucleated cells, applying the principles learned from well-studied models to other systems. LINC complex Cytoskeleton Nuclear movement Syncytia National Institute of Arthritis and Musculoskeletal and Skin Diseases http://dx.doi.org/10.13039/100000069 R56AR073193...

... the importance of the cytoskeleton, including actin filaments and microtubules, in rice development and environmental responses. Yet, reliable in vivo cytoskeleton markers are lacking in rice, which limits our knowledge of cytoskeletal functions in living cells. Therefore, we generated bright fluorescent marker...

... ). Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells . Cytoskeleton 69 , 738 - 750 . 10.1002/cm.21050 Nestor-Bergmann , A. , Goddard , G. and Woolner , S. ( 2014 ). Force and the spindle: mechanical cues in mitotic spindle...

... of a developmental blueprint that defines the polarized organization of the apical cytoskeleton in hair cells, including stereocilia distribution and elongation. Here, we report a role for multiple PDZ domain (MPDZ) protein during apical hair cell morphogenesis in mouse. We show that MPDZ is enriched at the hair...

...-C ). This tendency highlights the potential importance of the spatial distribution of cytoskeleton in determining morphological characteristics. We then used an isolated culture model of the epithelial rudiment of mouse embryonic submandibular gland (epiSMG) ( Nogawa and Takahashi, 1991 ), in which...

... migration – are reviewed, with a focus on Drosophila , a powerful model for studying these events. Cell adhesion Cytoskeleton Drosophila Morphogenesis During morphogenesis, the body is assembled and remodeled by cell shape changes and movements ( Gillard and Röper, 2020 ). These events...

...-characterized regulator of mesenchymal cell adhesion signaling, F-actin cytoskeleton remodeling and single cell migration, its role in epithelial tissue organization and mammary gland morphogenesis in vivo has not been investigated. Here, using a newly developed paxillin conditional knockout mouse model...

...-microtubule interactions, ensuring proper spindle morphology and accurate chromosome movement during oocyte maturation. Oocyte Meiosis Cytoskeleton Chromosome Reproduction Bub1b Acetylation of the lysine ε-amino group is a dynamic post-translational modification regulated by the opposing...

..., highlighting a key role for kinesin-13 proteins when centrosome activity is defective or absent. Cytoskeleton Microtubule dynamics Meiotic spindle Chromosome segregation Microtubule depolymerase Polar body extrusion Sexual reproduction relies on meiosis, a specialized type of cell division...

... extension Cytoskeleton Cell protrusions Extracellular matrix Proteases Morphogenesis How the neural tube (NT) forms is a central issue in developmental biology. Vertebrate neurulation is a complex morphogenetic process that requires the coordination of many cellular and molecular events...

... and a phenotype mimicking dilated cardiomyopathy. Vinculin Coronary vessel Epicardium Cytoskeleton Zebrafish The bulk of the vertebrate heart consists of cardiomyocytes and fibroblasts. In addition, the heart contains endothelial cells, which constitute the endocardium and coronary vessels...

... assignment. Mid1ip1l protein localizes to cortical F-actin aggregates, consistent with a direct role in cytoskeletal regulation. Our studies indicate that maternally provided aura ( mid1ip1l ) acts during the reorganization of the cytoskeleton at the egg-to-embryo transition and highlight the importance...

... ) Competing interests The authors declare no competing financial interests. 20 1 2014 14 8 2014 © 2014. Published by The Company of Biologists Ltd 2014 Axon retraction Cytoskeleton Stress fiber Synaptogenesis During neuronal development, the formation and maintenance...

... interests. 10 4 2014 16 7 2014 © 2014. Published by The Company of Biologists Ltd 2014 Cell migration Cytoskeleton Endocytosis C-jun N-terminal kinase Doublecortin Rab5 Mouse Cdkn1b During organogenesis, newly generated cells from the progenitors are allocated...

... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Cell asymmetries Body plan Oogenesis Intracellular transport Cytoskeleton Microtubules Motor proteins The transport of cargos by motors contributes...

... regulation of the cytoskeleton. * Author for correspondence ( peifer@unc.edu ) Competing interests statement The authors declare no competing financial interests. 30 7 2013 © 2013. Published by The Company of Biologists Ltd 2013 APC Axin Drosophila Chromosome...

... The authors declare no competing financial interests. 30 1 2013 © 2013. Published by The Company of Biologists Ltd 2013 Axon development Cytoskeleton Motoneurons Mouse embryo Neuromuscular junction Clip3 Cytoplasmic linker proteins, or CLIPs, define a family...

... for correspondence ( jan.traas@ens-lyon.fr ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd Phyllotaxis Auxin Cytoskeleton Biomechanics Meristem Morphogenesis Plant architecture...