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Keywords: Cyclopamine
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Journal Articles
Journal: Development
Development (2017) 144 (7): 1165–1176.
Published: 1 April 2017
... receptor . Nature   384 , 176 - 179 . 10.1038/384176a0 Mich , J. K. , Blaser , H. , Thomas , N. A. , Firestone , A. J. , Yelon , D. , Raz , E. and Chen , J. K. ( 2009 ). Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent . Dev...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (8): 1361–1371.
Published: 15 April 2010
... uki Dzip Hip Ptc1 Ptc2 Su(fu) Cyclopamine The vertebrate inner ear is a complex structure with asymmetries about all three body axes. These asymmetries arise early during ear development; by otic placode and vesicle stages, several otic genes are expressed asymmetrically...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (22): 3789–3799.
Published: 15 November 2008
...: Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA 12 9 2008 © 2008. 2008 Hedgehog Cardiac progenitor specification Cyclopamine Heart development Smoothened Zebrafish A principal goal of regenerative medicine is to convert naïve...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (17): 3419–3428.
Published: 1 September 2006
... Biology, Karolinska Institute, Box 240, S-17177 Stockholm,Sweden ‡ Present address: NIOB/KNAW Hubrecht Laboratorium, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands 5 7 2006 © 2006. 2006 BMP antagonist Cyclopamine Feedback signalling FGF Gremlin1 Hox gene expression Limb...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (16): 3643–3656.
Published: 15 August 2005
... the expression of Slit guidance molecules that then help to regulate glial cell position and axon guidance across the midline of the forebrain. 3 6 2005 ©2005. 2005 Zebrafish Cyclopamine Morpholino Axon guidance POC Chiasm Gfap Glia hedgehog slit you-too We have...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3243–3253.
Published: 15 July 2005
... the spinal cord but is also transmitted to the surrounding blastema. Cyclopamine treatment revealed that hedgehog signaling is not only required for DV patterning of the regenerating spinal cord but also had profound effects on the regeneration of surrounding, mesodermal tissues. Proliferation of tail...
Journal Articles
Journal: Development
Development (2004) 131 (11): 2521–2532.
Published: 1 June 2004
... for the proper regulation of Hh target genes in response to Hh signals. Cyclopamine and forskolin were dissolved in 100% dimethyl sulfoxide (DMSO)at 10 mM and 60.9 mM, respectively. Embryos were dechorinated with pronase at 50% epiboly and placed in 6 ml of embryo medium( Westerfield, 1993 ) containing 50 μM...
Journal Articles
Journal: Development
Development (2003) 130 (22): 5351–5362.
Published: 15 November 2003
... of neurogenin1 ( ngn1 ), a gene required for determination of DRG precursors. Cell transplantation experiments demonstrate that Hh acts directly on DRG neuron precursors. Blocking Hh pathway activation at later stages of embryogenesis with the steroidal alkaloid, cyclopamine,further reveals that the requirement...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1549–1564.
Published: 15 April 2003
... that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 has minor roles as a repressor or activator of Hh targets. Forebrain patterning Hedgehog signaling Adaxial cells floor plate cyclopamine Morpholino © 2003. 2003 14 11 2002 * Author for correspondence (e...
Journal Articles
Journal: Development
Development (2003) 130 (1): 15–28.
Published: 1 January 2003
... Cerebellum Sonic hedgehog Proliferation Cyclopamine Medulloblastoma Nmyc Neural precursor TRRAP Mouse Signaling by the hedgehog family of secreted glycoproteins has been highly conserved through evolution ( Ingham and McMahon, 2001 ). Hedgehog activity is required for fundamental processes...