...Cai-Li Bi; Qian Cheng; Ling-Yue Yan; Hong-Yan Wu; Qiang Wang; Ping Wang; Lin Cheng; Rui Wang; Lin Yang; Jian Li; Feng Tie; Hao Xie; Ming Fang ABSTRACT The evolutionarily conserved C-terminal binding protein (CtBP) has been well characterized as a transcriptional co-repressor. Herein, we report...

... more than one, with Drosophila Brinker (Brk) recruiting the co-repressors CtBP and Groucho (Gro), in addition to possessing a third repression domain, 3R. Previous studies indicated that Gro is sufficient for Brk to repress targets in the wing, questioning why it should need to recruit CtBP, a short...

...Paolo Struffi; Maria Corado; Meghana Kulkarni; David N. Arnosti The Drosophila Knirps protein is a short-range transcriptional repressor that locally inhibits activators by recruiting the CtBP co-repressor. Knirps also possesses CtBP-independent repression activity. The functional importance...

... 06 1999 © 1999 by Company of Biologists 1999 CtBP XTcf-3 Lef/Tcf Transcriptional repression Wnt pathway Xenopus Studies in many systems have established the importance of the Wnt pathway in regulating numerous processes during embryonic development, as well as cell...