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Keywords: Cortex
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (15): dev201830.
Published: 1 August 2023
... to distinct NGC subtypes and positioned in different cortical layers ( Fig. 5 B, Table S15 ). Conversely, when the sg Tox2 GFP plasmid was co-electroporated, we observed a complete depletion of NGCs in the cortex ( Fig. 5 A). Concomitantly, we observed cell distribution alterations in the hypothalamus at P10...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (11): dev199409.
Published: 28 May 2021
...Frédéric Causeret; Matthieu X. Moreau; Alessandra Pierani; Oriane Blanquie ABSTRACT Cajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (18): dev189738.
Published: 28 September 2020
... malformations. Agenesis Axonal guidance and plasticity Callosal projecting neurons Corpus Callosum Cortex Development Interhemispheric The corpus callosum (CC) is the major axonal tract of the mammalian brain and the principal path transferring information between hemispheres ( Fame et al...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (14): dev185033.
Published: 22 July 2020
...Pietro Fazzari; Niall Mortimer; Odessa Yabut; Daniel Vogt; Ramon Pla ABSTRACT Cortical interneurons (CINs) originate in the ganglionic eminences (GEs) and migrate tangentially to the cortex guided by different attractive and repulsive cues. Once inside the cortex, the cellular and molecular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (21): 3968–3977.
Published: 1 November 2017
.../ Summary: mRNA electroporation is a powerful new method for functional studies in neonatal and adult neural stem cells as well as postmitotic neurons. Adult neurogenesis Subventricular zone Olfactory bulb Cortex Dicer microRNA pathway Manipulation of gene expression in the brain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3744–3754.
Published: 15 October 2017
.... Islet Chemoattractant Radial migration Nrp2 Sema3a Neural development Cortex Mouse Human Pancreatic islets are named for their most characteristic feature: islets are endocrine cell clusters dispersed throughout an abundant sea of exocrine tissue. The molecular and signaling origins...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (6): 952–957.
Published: 15 March 2017
... and the resulting pathology. Zika Cortex iPSC Microcephaly Organoids The rapidly advancing field of stem cell biology continually provides new insights into basic biology and human disorders, as well as innovative approaches to develop new patient treatment strategies. In the past 10 years, human...
Journal Articles
Journal: Development
Development (2016) 143 (6): 978–982.
Published: 15 March 2016
..., epidermal and cortical cells do not form narrow, ring-like preprophase bands (PPBs), which are plant-specific, cytoskeletal structures that predict the position of the division plane before mitosis. The results indicate that in the cortex but not in the epidermis, division plane positioning and patterning...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (1): 140–150.
Published: 1 January 2015
...Katrin Gerstmann; Daniel Pensold; Judit Symmank; Mukhran Khundadze; Christian A. Hübner; Jürgen Bolz; Geraldine Zimmer The phenotype of excitatory cerebral cortex neurons is specified at the progenitor level, orchestrated by various intrinsic and extrinsic factors. Here, we provide evidence...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (17): 3370–3377.
Published: 1 September 2014
... Attribution License ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. 5-HT6 receptor Migration Serotonin Cortex Cdk5 Mouse Fig. 1. In vivo downregulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 11–16.
Published: 1 January 2014
...Zoltán Molnár; Alex Pollen The human cerebral cortex is generally considered the most complex organ, and is the structure that we hold responsible for the repertoire of behavior that distinguishes us from our closest living and extinct relatives. At a recent Company of Biologists Workshop...
Journal Articles
Journal: Development
Development (2012) 139 (20): 3870–3879.
Published: 15 October 2012
...Marianeli Rodriguez; Jeonghoon Choi; Sungjin Park; Shanthini Sockanathan The mammalian cortex is a multilaminar structure consisting of specialized layer-specific neurons that form complex circuits throughout the brain and spinal cord. These neurons are generated in a defined sequence dictated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (10): 1887–1899.
Published: 15 May 2007
... formation, we conditionally ablated Olig2 in a spatiotemporally controlled manner. In the Olig2 -ablated cortex and spinal cord, the formation of astrocytes in the white matter is severely compromised. Temporally controlled mutagenesis revealed that postnatal Olig2 function is required for astrocyte...
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (24): 6131–6140.
Published: 15 December 2004
.... Assimacopoulos, S., Grove, E. A. and Ragsdale, C. W. ( 2003 ). Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. J. Neurosci. 23 , 6399 -6403. Bertrand, N., Castro, D. S. and Guillemot, F. ( 2002 ). Proneural genes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (21): 5441–5448.
Published: 1 November 2004
... is required for normal brain size, and regulates lateral expansion of the proliferative zone in the developing cortex and hippocampus. In its absence, proliferation of stem cells in the ventricular zone (VZ) is compromised. In early cortical progenitors, Id4 is required for the normal G1-S transition...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (10): 2275–2287.
Published: 15 May 2003
... of the cerebral cortex and meninges. These heterotopias are frequently observed as microscopic abnormalities in the brains of individuals with central nervous system (CNS) malformations and epilepsy. Previous work has demonstrated that the function of Emx2 , which encodes a homeodomain transcription factor...
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (19): 4483–4495.
Published: 1 October 2002
... organization of microtubules without massive depolymerization. These results suggest that MUK/DLK/ZPK and JNK regulate radial cell migration via microtubule-based events. *Author for correspondence (e-mail: sh3312@med.yokohama-cu.ac.jp ) 27 6 2002 © 2002. 2002 Cortex JNK Microtubules...