...Shashwati Bhattacharya; Caitlin Hyland; Matthias M. Falk; M. Kathryn Iovine ABSTRACT The gap junction protein Connexin 43 (Cx43) contributes to cell fate decisions that determine the location of fin ray joints during regeneration. Here, we provide insights into how Cx43, expressed medially...

...David Y. Rhee; Xiao-Qing Zhao; Richard J. B. Francis; Guo Ying Huang; John D. Mably; Cecilia W. Lo Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that suggest defects in epicardial epithelial...

... and maintenance of pregnancy. Although uterine angiogenesis is known to be influenced by the steroid hormones estrogen (E) and progesterone(P), the underlying molecular pathways remain poorly understood. Here, we report that the expression of connexin 43 (Cx43), a major gap junction protein, is markedly enhanced...

...Xin Xu; Richard Francis; Chih Jen Wei; Kaari L. Linask; Cecilia W. Lo Connexin 43 knockout (Cx43α1KO) mice have conotruncal heart defects that are associated with a reduction in the abundance of cardiac neural crest cells (CNCs) targeted to the heart. In this study, we show CNCs can respond...

... (ODDD) is an autosomal dominant disorder characterized by pleiotropic developmental anomalies of the limbs, teeth, face and eyes that was shown recently to be caused by mutations in the gap junction protein alpha 1 gene ( GJA1 ), encoding connexin 43 (Cx43). In the course of performing an N-ethyl-N...

.... Biol . 171 , 317 – 329 . 10.1006/dbio.1995.1284 Waldo , K. L. , Lo , C. W. and Kirby , M. L. ( 1999 ). Connexin 43 expression reflects neural crest patterns during cardiovascular development . Dev. Biol . 208 , 307 - 323.3 10.1006/dbio.1999.9219 Pax3...

... stained with an antibody to connexin 43. It is clear that there are many punctate gap junctions. indeed a greater number than normally found in con-trois of the same age. Furthermore, the junctions exist entirely as punctate spots apparently randomly distributed along the intercellular opposing membranes...