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Keywords: Compensatory proliferation
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Journal Articles
Journal: Development
Development (2016) 143 (16): 2907–2919.
Published: 15 August 2016
... stress-response pathway promoting injury-induced apoptosis and compensatory proliferation. A central question remaining unanswered is how both responses are balanced by activation of a single pathway. Signalling through the Janus kinase/Signal transducers and activators of transcription (JAK/STAT...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (16): 2740–2751.
Published: 15 August 2015
... eye to investigate the mechanisms that trigger quiescent cells to re-enter the cell cycle and proliferate in response to tissue damage. We discovered that Hippo signaling regulates compensatory proliferation after extensive cell death in the developing eye. Scalloped and Yorkie, transcriptional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (7): 1169–1177.
Published: 1 April 2009
... and pattern. Thus, the surviving cells have to undergo additional proliferation to compensate for the cell loss. The finding that apoptotic cells ectopically express dpp and wg suggested that ectopic Dpp/Wg signalling might be responsible for compensatory proliferation. We have tested this hypothesis...
Includes: Supplementary data