1-20 of 34
Keywords: Collagen
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2023) 150 (16): dev201640.
Published: 17 August 2023
... Niche Perlecan Collagen Integrin Laminin National Institutes of Health R21HD103989 R35GM118081 American Cancer Society http://dx.doi.org/10.13039/100000048 PF-16-098-01-DDC Stem cells must balance proliferation and differentiation in order to meet...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200456.
Published: 16 May 2022
... composition and mechanical properties of the basement membrane underlying the follicle epithelium of Drosophila egg chambers. We find that the Laminin and Collagen IV networks largely persist in the absence of the other components. Moreover, we show that Perlecan and Collagen IV, but not Laminin or Nidogen...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (13): dev199559.
Published: 1 July 2021
... is to secrete collagen-containing bone matrix. However, it remains unclear how the dynamics of collagen trafficking is regulated during skull development. Here, we reveal the regulatory mechanisms of ciliary and golgin proteins required for intramembranous ossification. During normal skull formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (18): dev190983.
Published: 18 September 2020
... that failed to be secreted in both mutants was a type II collagen (Col2a1). Col2a1 is normally secreted by notochord sheath cells, alongside which LECs migrate. col2a1a mutants displayed defects in the migratory behaviour of LECs and failed lymphangiogenesis. These studies thus identify Col2a1 as a key cargo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (23): dev185306.
Published: 2 December 2019
... induces fibroblast migration in 3D extracellular matrix (ECM) through regulation of actomyosin cytoskeleton and promotes force-mediated collagen remodeling by mammary fibroblasts. Moreover, FGF2 regulates production of ECM proteins by mammary fibroblasts, including collagens, fibronectin, osteopontin...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (2): 313–320.
Published: 15 January 2017
... at the age of 10 weeks and expression remained at similar levels at 12 months. In Mkx −/− mice, age-dependent expansion of the PDL at the maxillary first molar (M1) furcation area was observed. Transmission electron microscopy (TEM) revealed that Mkx −/− mice presented collagen fibril degeneration in PDL...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (5): 983–993.
Published: 1 March 2015
... regulating collagen maturation and organization, uncouples the balance between the amount of myofibers and that of muscle connective tissue (MCT). We show that Lox secreted from the myofibers attenuates TGFβ signaling, an inhibitor of myofiber differentiation and promoter of MCT development. We further...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4602–4613.
Published: 15 November 2013
..., and defects in its structure correlate with a subset of muscular dystrophies. Col22a1 encodes the MTJ component collagen XXII, the function of which remains unknown. Here, we have cloned and characterized the zebrafish col22a1 gene and conducted morpholino-based loss-of-function studies in developing embryos...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (23): 4473–4483.
Published: 1 December 2012
...Lital Bentovim; Roy Amarilio; Elazar Zelzer Collagen production is fundamental for the ontogeny and the phylogeny of all multicellular organisms. It depends on hydroxylation of proline residues, a reaction that uses molecular oxygen as a substrate. This dependency is expected to limit collagen...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (8): 1507–1519.
Published: 15 April 2011
... Sox9 Chondrocytes Collagen Conditional knockout Transcriptional regulation Mouse During development, the limb skeleton is created through endochondral bone formation. Mesenchymal cells initially undergo condensation, which is followed by the differentiation of prechondrogenic cells within...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (24): 4261–4269.
Published: 15 December 2010
... cloning revealed that stumpy was the zebrafish homolog of the atypical FACIT collagen collagenXIXa1 ( colXIX ). colXIX expression was observed in a temporal and spatial pattern, consistent with a role in motor axon guidance at intermediate targets. Knocking down zebrafish ColXIX phenocopied the stumpy...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (23): 5883–5895.
Published: 1 December 2004
... in trabecular bone occur independently of the improper cartilage ECM degradation caused by Mmp13 deficiency in late hypertrophic chondrocytes. Our studies identified the two major components of the cartilage ECM, collagen type II and aggrecan, as in vivo substrates for MMP13. We found that degradation...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2000) 127 (4): 821–830.
Published: 15 February 2000
... procollagen IIA (200 pg/injection). VMZ explants were excised at early gastrula and cultured until stage (G) RT-PCR analysis of VMZ explants treated as above; the expression of the dorsal marker α -actin and EF-1α were analyzed by RT-PCR. Note that full-length collagen, but not the CR domain alone, can...
Journal Articles
Journal: Development
Development (1995) 121 (8): 2471–2478.
Published: 1 August 1995
... by a pathway of heterochronic genes that includes the relatively direct regulatory gene, lin-29 , and upstream genes lin-4, lin-14 and lin-28 . Using northern analysis to detect endogenous collagen mRNA levels and collagen/lacZ reporter constructs to monitor collagen transcriptional activity, we show...
Journal Articles
Journal: Development
Development (1994) 120 (2): 425–432.
Published: 1 February 1994
... and chemotaxic gradients. Recently, in vitro cell adhesion studies indicated that isolated nematocytes could bind to substrata coated with isolated hydra mesoglea, fibronectin and type IV collagen. Under these conditions, nematocytes could be observed to migrate on some of these extracellular matrix components...
Journal Articles
Journal: Development
Development (1992) 116 (3): 531–541.
Published: 1 November 1992
...Thomas Lallier; Gabrielle Leblanc; Kristin B. Artinger; Marianne Bronner-Fraser ABSTRACT We have used a quantitative cell attachment assay to compare the interactions of cranial and trunk neural crest cells with the extracellular matrix (ECM) molecules fibronectin, laminin and collagen types I...