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Keywords: Co-repressor
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Journal Articles
Journal: Development
Development (2016) 143 (17): 3074–3084.
Published: 1 September 2016
... complex, and are dispensable for the maintenance of pluripotency. Sall4 NuRD ES cells Enhancer Transcription factor Co-repressor Embryonic stem cells (ESCs) have the potential to form any somatic cell type in the adult organism; that is, they are pluripotent. In order to properly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (20): 4256–4265.
Published: 15 October 2013
...Priyanka Upadhyai; Gerard Campbell Transcriptional repressors function primarily by recruiting co-repressors, which are accessory proteins that antagonize transcription by modifying chromatin structure. Although a repressor could function by recruiting just a single co-repressor, many can recruit...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (3): 505–512.
Published: 1 February 2013
... levels by chromatin-modifying, co-repressor complexes provides transcriptional fine-tuning that drives development. In addition to repressing transcription or keeping genes poised on the verge of transcription, repressors can act to fine-tune levels of active gene expression. This modulation acts...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3649–3659.
Published: 1 August 2004
... that encode proteins with structural relation to GRO/TUP1-like co-repressors. Using a yeast-based screen we found that STY interacts with several transcription factors, suggesting that STY, like GRO/TUP1, forms complexes in vivo. Proteins of the YABBY family, characterised by containing a partial HMG domain...
Journal Articles
Journal: Development
Development (2004) 131 (1): 3–14.
Published: 1 January 2004
...J. Susie Zoltewicz; Nicola J. Stewart; Ricky Leung; Andrew S. Peterson Atrophins are evolutionarily conserved proteins that are thought to act as transcriptional co-repressors. Mammalian genomes contain two atrophin genes. Dominant polyglutamine-expanded alleles of atrophin 1 have been identified...
Journal Articles
Journal: Development
Development (2002) 129 (1): 253–263.
Published: 1 January 2002
...., 1994 ; Riechmann and Meyerowitz, 1998 ; Nole-Wilson and Krizek, 2000 ). LUG encodes a glutamine-rich protein with seven WD repeats and was predicted to act as a transcriptional co-repressor ( Conner and Liu, 2000 ). lug and ap2 mutations enhance each others’ effects with respect to floral organ...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4361–4370.
Published: 1 November 2001
...Yiorgos Apidianakis; Diane Grbavec; Stefano Stifani; Christos Delidakis Groucho (Gro) is the founding member of a family of transcriptional co-repressors that are recruited by a number of different transcription factors. Drosophila has a single gro gene, whose loss of function affects processes...