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Keywords: Cleft lip
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200181.
Published: 26 May 2022
... Tgfβ Cleft palate Cleft lip Craniofacial Live imaging Fusion Actomyosin Cell adhesion Non-muscle myosin II NMIIA Mouse National Institute of Dental and Craniofacial Research http://dx.doi.org/10.13039/100000072 R01DE025877 F32DE030367 R35DE031926 UCSF: University...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev187369.
Published: 30 April 2020
...SungKyoung Lee; Matthew J. Sears; Zijun Zhang; Hong Li; Imad Salhab; Philippe Krebs; Yi Xing; Hyun-Duck Nah; Trevor Williams; Russ P. Carstens; Sally Dunwoodie; John Wallingford ABSTRACT Cleft lip is one of the most common human birth defects. However, there remain a limited number of mouse models...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (12): dev174888.
Published: 17 June 2019
...://www.biologists.com/user-licence-1-1/ Summary: Using single cell RNA-seq, novel cell populations are identified that are associated with fusion of the lip/primary palate, developing a model that predicts molecular and cellular behaviours during fusion. Cleft lip Primary palate Palate fusion Single...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (11): 2082–2091.
Published: 1 June 2017
...Joshua L. Everson; Dustin M. Fink; Joon Won Yoon; Elizabeth J. Leslie; Henry W. Kietzman; Lydia J. Ansen-Wilson; Hannah M. Chung; David O. Walterhouse; Mary L. Marazita; Robert J. Lipinski Cleft lip is one of the most common human birth defects, yet our understanding of the mechanisms that regulate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1059–1063.
Published: 1 March 2014
...., 2011 ). We targeted SHH signaling because of its known role in controlling mesenchymal growth zones, but similar predictions could be made of other genes or pathways that affect the relative growth of facial prominences and are implicated in cleft-lip etiology ( Brugmann et al., 2007 ; Dixon et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1821–1830.
Published: 15 May 2012
...Yong-Ri Jin; Xiang Hua Han; Makoto M. Taketo; Jeong Kyo Yoon Outgrowth and fusion of the lateral and medial nasal processes and of the maxillary process of the first branchial arch are integral to lip and primary palate development. Wnt9b mutations are associated with cleft lip and cleft palate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (18): 3161–3171.
Published: 15 September 2009
...Lanying Song; Yunhong Li; Kai Wang; Ya-Zhou Wang; Andrei Molotkov; Lifang Gao; Tianyu Zhao; Takashi Yamagami; Yongping Wang; Qini Gan; David E. Pleasure; Chengji J. Zhou Neither the mechanisms that govern lip morphogenesis nor the cause of cleft lip are well understood. We report that genetic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (19): 4647–4660.
Published: 1 October 2002
... for cleft lip is the failure of individual components of the upper embryonic face (facial prominences) to meet and fuse at the appropriate time. The primary palate consists of those facial prominences that come together to form the upper lip. Failure of fusion to occur in the human primary palate results...