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Keywords: Chick embryo
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200295.
Published: 16 May 2022
... these. Using experimental manipulation of early chick embryos, including misexpression of an inducer (VG1 or ACTIVIN) and an inhibitor (BMP4), we test two alternative models for their ability to explain how the site of primitive streak formation is positioned relative to the rest of the embryo. In one model...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev162578.
Published: 17 October 2018
.... Aortic arches Chick embryo Computational modeling Heart development Hemodynamics Mechanical forces Congenital heart defects (CHDs) constitute the most severe form of a birth defect, accounting for 24% of deaths from developmental abnormalities ( Mozaffarian et al., 2016 ). Abnormal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (12): dev159657.
Published: 11 June 2018
... to expression from unaffected loci. Chick embryos offer the opportunity to perform conditional miRNA KD experiments using antagomirs that simultaneously inhibit the mature form of all miR-133 family members produced ( Goljanek-Whysall et al., 2014 ). This has uncovered a crucial function of miR-133...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (4): dev160325.
Published: 21 February 2018
... to promoter regions of actively transcribed genes to control H3K9 demethylation. Chick embryo Epigenetic marks Histone modification Otic placode Transcription factor In the developing embryo, multipotent progenitors are able to maintain their identity and gene expression programmes despite...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (15): 2810–2823.
Published: 1 August 2017
... the induction and patterning of chick sensory placodes. Chick embryo Quail graft Cell fate Sense organs Sensory ganglia Transcriptional networks Signalling Gene regulatory network During early development, many fate decisions are controlled by inductive interactions, whereby an inducing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2194–2205.
Published: 15 June 2016
...-migratory NC cells, are required for NC delamination in Xenopus and chick embryos, whereas they do not affect the motile properties of migratory NC cells. Dact1/2 inhibit Wnt/β-catenin signalling upstream of the transcriptional activity of T cell factor (TCF), which is required for EMT to proceed. Dact1/2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (10): 1742–1752.
Published: 15 May 2016
.... During the hypoxic stage, a large number of neural crest cells arise from the head neural tube by epithelial-to-mesenchymal transition (EMT). As EMT-like cancer dissemination can be promoted by hypoxia, we investigated whether hypoxia contributes to embryonic EMT. Using chick embryos, we show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (15): 2686–2695.
Published: 1 August 2015
... Chick embryo Wnt signaling The kidney is a vital, bilateral organ that is the central component of the body's excretory system. Three kidneys are formed sequentially during mammalian and avian development: the largely non-functional pronephros, the embryonic/fetal mesonephros and the functional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (18): 3605–3611.
Published: 15 September 2014
... development. Here, we have developed novel molecular tools to characterize muscle cell fusion during chick embryo development. We show that all cell populations arising from somites fuse, but each with unique characteristics. Fusion in the trunk is slow and independent of fiber length. By contrast...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (17): 3378–3387.
Published: 1 September 2014
.... MicroRNA inhibition in chick embryos leads to increased BAF60a or BAF60b levels, a concomitant switch in BAF/Brg1 subunit composition and delayed myogenesis. The phenotypes are mimicked by sustained BAF60a or BAF60b expression and are rescued by morpholino knockdown of BAF60a or BAF60b. This suggests...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (16): 3266–3276.
Published: 15 August 2014
.... , Sanz-Ezquerro J.-J. , Farrell E. R. , Mathers J. , Keyse S. M. , Storey K. , Tickle C. ( 2003 ). Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos . Curr. Biol. 13 , 1009 - 1018 . 10.1016/S0960-9822(03)00381-6 Fior R...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2057–2063.
Published: 15 May 2014
... ) Competing interests The authors declare no competing financial interests 6 1 2014 13 3 2014 © 2014. Published by The Company of Biologists Ltd 2014 Somite WNT Dermomyotome Chick embryo Somites are blocks of cells sequentially generated through the epithelialization...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4565–4573.
Published: 15 November 2013
... and coverslipped using methacrylate mounting medium. Wnt signaling Chick embryo Kidney Mesonephros Podocyte Renal vesicle Vertebrate kidneys are composed of functional units called nephrons ( Saxen, 1987 ; Dressler, 2006 ). Each nephron has several distinct functional...
Journal Articles
Journal: Development
Development (2013) 140 (8): 1819–1829.
Published: 15 April 2013
...Britannia M. Fleming; Ronit Yelin; Richard G. James; Thomas M. Schultheiss The intermediate mesoderm (IM) is the embryonic source of all kidney tissue in vertebrates. The factors that regulate the formation of the IM are not yet well understood. Through investigations in the chick embryo...
Journal Articles
Journal: Development
Development (2012) 139 (22): 4143–4151.
Published: 15 November 2012
... specification Chick embryo Hox genes Kidney Mesoderm patterning Nephric duct Repression of duct formation may have played an important role during vertebrate kidney evolution. In the embryo of the hagfish, considered to be the most primitive extant vertebrate, the IM does not become regionalized...
Journal Articles
Journal: Development
Development (2012) 139 (22): 4232–4238.
Published: 15 November 2012
... of the primary hypoblast in the chick . J. Embryol. Exp. Morphol. 52 , 79 - 88 . Bachvarova R. F. , Skromne I. , Stern C. D. ( 1998 ). Induction of primitive streak and Hensen's node by the posterior marginal zone in the early chick embryo . Development 125 , 3521 - 3534...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (9): 1680–1690.
Published: 1 May 2012
...: to serve as a mechanically passive substrate for the crawling mesoderm and to secrete various growth factors necessary for cardiac specification and differentiation. Here, using computational modeling and experiments on chick embryos, we present evidence supporting an active mechanical role...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (22): 3801–3811.
Published: 15 November 2010
.... Using chick embryos cultured ex ovo, we measured: (1) changes in tissue morphology in living embryos using optical coherence tomography (OCT); (2) morphogenetic strains (deformations) through the tracking of tissue labels; and (3) regional tissue stresses using changes in the geometry of circular wounds...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (6): 881–890.
Published: 15 March 2010
... interests statement The authors declare no competing financial interests. 15 1 2010 © 2010. 2010 Fgf Chick embryo Differentiation Embryonic stem cells Mouse Retinoic acid Differentiating mouse embryonic stem (ES) cells first downregulate pluripotency genes and transit...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (15): 2579–2589.
Published: 1 August 2009
.... * Author for correspondence (e-mail: takashi.mikawa@ucsf.edu ) 18 5 2009 © 2009. 2009 Eye Retina Pigmented epithelium Electroporation Sox genes Chick embryo The retina originates from a bilateral evagination of the forebrain, called the optic vesicle (OV). As the overlying...
Includes: Supplementary data