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Keywords: Cerebellar development
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Journal Articles
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Neural development
Journal: Development
Development (2019) 146 (20): dev177550.
Published: 10 October 2019
...Jennifer K. Ocasio; Rolf Dale P. Bates; Carolyn D. Rapp; Timothy R. Gershon ABSTRACT Cerebellar development requires regulated proliferation of cerebellar granule neuron progenitors (CGNPs). Inadequate CGNP proliferation causes cerebellar hypoplasia whereas excessive CGNP proliferation can cause...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3686–3697.
Published: 15 October 2017
...), raising questions regarding its role as a regulator of neural progenitor cell cycle progression in cerebellar development. To characterize in vivo the function of ZFP423 in neurogenesis, we analyzed allelic murine mutants in which distinct functional domains are deleted. One deletion impairs mitotic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (1): 133–146.
Published: 1 January 2016
... organisation and impaired proliferation of cerebellar progenitors. Cerebellar development Pals1 Mpp5 Polarity complex proteins Germinal zones Mouse Bergmann glia A mature cerebellum includes Purkinje cells (PCs), cerebellar granule neurons (CGNs), deep cerebellar nuclei neurons (DCNs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (19): 3929–3937.
Published: 1 October 2006
... to their mature location in the inner granule layer. In this study, we examined the expression of D type cyclins in GNPs during cerebellar development and showed that GNPs in early development expressed only cyclin D1, whereas later GNPs expressed both cyclins D1 and D2. Coinciding with the period of cyclin D1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3281–3291.
Published: 15 July 2005
... development. * Author for correspondence (e-mail: xliu@mednet.ucla.edu ) 5 5 2005 ©2005. 2005 PTEN Bergmann glia Cerebellar development Mouse Precise neuronal functions require highly ordered cell proliferation,differentiation, migration and synaptic specificity...
Journal Articles
Journal: Development
Development (2004) 131 (13): 3159–3168.
Published: 1 July 2004
... neurones, the internal granular layer (IGL). Neurogenesis of the Purkinje cells occurs within the ventricular zone during the early phases of cerebellar development,Purkinje cell precursors migrate to form the first cell layer and thereby set up the framework for the cerebellar cortex. Concomitantly...
Journal Articles
Journal: Development
Development (2003) 130 (15): 3359–3368.
Published: 1 August 2003
...; and (5) loss of Rb deficient CNS precursor cells is mediated by p53-independent apoptosis. * Author for correspondence (e-mail: silvia.marino@usz.ch ) 16 4 2003 © 2003. 2003 Cre-LoxP system Cerebellar development Rb Engrailed-2 p107 Granule cell Purkinje cell Mouse...
Journal Articles
Journal: Development
Development (2003) 130 (1): 29–43.
Published: 1 January 2003
... that precise spatio-temporal regulation of TAG-1 and F3/contactin expression is critical for normal cerebellar morphogenesis. † Authors for correspondence (e-mail: G.Gennarini@tno.it and A.J.Furley@Sheffield.ac.uk ) 3 10 2002 © 2003. 2003 Cerebellar development Neurite growth...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4217–4227.
Published: 1 November 2001
... disruption of two negative regulators of Rac, Abr and Bcr , in mice leads to specific abnormalities in postnatal cerebellar development. Mutants exhibit granule cell ectopia concomitant with foliation defects. We provide evidence that this phenotype is causally related to functional and structural...