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Keywords: Cell survival
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Journal Articles
Journal: Development
Development (2018) 145 (20): dev164046.
Published: 24 October 2018
... binds to LTK. Taken together, these results suggest that LTK in neural crest cells interacts with midkine emanating from the non-neural ectoderm to promote cell survival, revealing a new signaling pathway that is essential for neural crest development. * Author for correspondence ( mbronner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (9): dev156018.
Published: 25 April 2018
... TIR-NBS-LRR Sarm MyD88 NF-κB Dorsal Wek JNK FoxO Cell death Cell survival Cell fate Cell proliferation Structural plasticity Signalling The Drosophila gene Toll is possibly the only gene associated with two Nobel Prizes: it was discovered as one of the key genes determining...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2907–2919.
Published: 15 August 2016
... damage, JAK/STAT signalling and its effector Zfh2 promote the survival of JNK-signalling cells in Drosophila imaginal discs, thereby limiting tissue damage and facilitating systemic responses. JAK/STAT JNK Cell survival Compensatory proliferation Cancer Injury-induced apoptosis Eiger Cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (24): 5379–5391.
Published: 15 December 2011
.... , Kockel L. , Duchek P. , Luque C. M. , Rørth P. , Perrimon N. ( 2004 ). The PDGF/VEGF Receptor controls blood cell survival in Drosophila . Dev. Cell 7 , 73 – 84 . Buttitta L. A. , Edgar B. A. ( 2007 ). Mechanisms controlling cell cycle exit upon terminal...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (13): 2321–2329.
Published: 1 July 2008
...-catenin/Wnt signaling in dermal development. * Author for correspondence (e-mail: rpa5@case.edu ) 10 5 2008 © 2008. 2008 Dermis Cell fate Cell survival Skin Sternum Identifying the molecular controls of dermal cell fate from diverse origins in the mammalian embryo...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1443–1451.
Published: 1 April 2007
... upregulation, in addition to being necessary for the nuclear translocation of Mdm2. Inhibition of either mTOR or Mdm2 is sufficient to block cell survival induced by Hgf-Met in vitro. Moreover, in vivo inhibition of mTOR downregulates Mdm2 protein levels and induces p53-dependent apoptosis. Our studies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4771–4781.
Published: 1 December 2006
... concerning the genes required for survival during the early cell-proliferation phase. Here, we show that Lobe ( L ) and the Notch (N) ligand Serrate ( Ser ), which are both involved in ventral eye growth, are required for cell survival in the early eye disc. We observed that the loss-of-ventral-eye phenotype...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (12): 2435–2445.
Published: 15 June 2006
... found that Fgf8 is necessary for Pea3 expression within the AHF itself, and may also modulate Bmp4 expression levels. * Author for correspondence (e-mail: e.meyers@cellbio.duke.edu ) 18 4 2006 © 2006. 2006 Fgf8 Anterior heart field Cardiogenesis Cell Survival...
Journal Articles
Journal: Development
Development (2006) 133 (10): 1871–1880.
Published: 15 May 2006
... non-autonomous cell survival by controlling Diap1 protein levels. Further characterization of the vps25 mutant phenotype may help to identify the postulated receptor of the Hippo pathway and the cell survival signaling pathway. Human ESCRT components, most notably TSG101 (Vps23p), have been...
Journal Articles
Journal: Development
Development (2006) 133 (6): 1079–1089.
Published: 15 March 2006
... a transient phase of cell death, which affects most, but not all adenohypophyseal cells. Surviving cells form a smaller pituitary rudiment,lack expression of specific adenohypophyseal marker genes ( pit1,neurod ), while expressing others ( lim3, pitx3 ), and display an ultrastructure reminiscent of precursor...
Journal Articles
Journal: Development
Development (2006) 133 (3): 517–528.
Published: 1 February 2006
.... is supported by EU BioTech-Grant QLRT-2002-01141. A number of candidate genes have been previously identified as Shh responsive and involved in cell survival and advancing the cell cycle. Bcl2 is induced in keratinocytes ( Bigelow et al.,2004 ; Regl et al.,2004 ) and we demonstrate an upregulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4545–4553.
Published: 15 September 2004
... cells and pole cell-specific expression of wun2 rescued the pole cell death phenotype of the maternal wun2 mutant, suggesting that wun2 activity in pole cells is required for their survival. Furthermore, we obtained genetic evidence that pole cell survival requires a proper balance of LPP activity...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3681–3692.
Published: 1 August 2004
... Adenohypophysis Neurohypophysis Zebrafish Lia Cell survival Cell specification Apoptosis Sonic Hedgehog © 2004. 2004 21 4 2004 † Present address: University of Sheffield, Department of Biomedical Science,Firth Court, Western Bank, Sheffield S10 2TN, UK * Present address...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4919–4929.
Published: 15 October 2003
... and glypican. J. Cell Biol. 133 , 405 -416. Storm, E. E., Rubenstein, J. L. and Martin, G. R. ( 2003 ). Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain. Proc. Natl. Acad. Sci. USA 100 , 1757 -1762. Topczewski, J., Sepich, D. S...
Journal Articles
Journal: Development
Development (2001) 128 (20): 4011–4020.
Published: 15 October 2001
... of a myogenic regulatory gene, qmf1 , in the somite dermatome of avian embryos. Genes Dev . 4 , 567 -581. Charrier, J. B., Teillet, M.-A., Lapointe, F. and Le Douarin, N. M. ( 1999 ). Defining subregions of Hensen’s node essential for caudalward movement, midline development and cell survival...
Journal Articles
Journal: Development
Development (2001) 128 (19): 3819–3830.
Published: 1 October 2001
... conclude that the majority of the cell number differences between wild-type and Igf2 +m/−p mice can be accounted for by modification of cell survival and proliferation during the period (E9 to E10) of post-implantation development. The control of growth requires a complex set of interactions operating...