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Keywords: Cell migration
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Journal Articles
Journal: Development
Development (2022) 149 (19): dev200278.
Published: 3 October 2022
... hematopoiesis in zebrafish. Hematopoietic niche Stromal cells Cell migration Protocadherin Somite Zebrafish Institut Pasteur http://dx.doi.org/10.13039/501100003762 Centre National de la Recherche Scientifique http://dx.doi.org/10.13039/501100004794 Fondation pour...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (15): dev200068.
Published: 8 August 2022
... Cousin , H. ( 2017 ). Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin . Mech. Dev. 148 , 79 - 88 . 10.1016/j.mod.2017.04.006 El Ghouzzi , V. , Le Merrer , M. , Perrin-Schmitt , F. , Lajeunie...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200647.
Published: 19 May 2022
...Naoya Yamaguchi; Holger Knaut ABSTRACT Cell-extracellular matrix interactions have been studied extensively using cells cultured in vitro . These studies indicate that focal adhesion (FA)-based cell-extracellular matrix interactions are essential for cell anchoring and cell migration. Whether FAs...
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200001.
Published: 2 December 2021
..., leading to increased speed of migration. Moreover, overactivation of Rac1, due to Piezo1 inhibition, counteracts cell migration inhibitory signals by Semaphorin 3A and Semaphorin 3F, generating aberrant neural crest invasion in vivo . Thus, we find that, for directional migration in vivo , neural crest...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (7): dev191767.
Published: 1 April 2021
...Jessica Stock; Andrea Pauli ABSTRACT Self-organization is a key feature of many biological and developmental processes, including cell migration. Although cell migration has traditionally been viewed as a biological response to extrinsic signals, advances within the past two decades have...
Journal Articles
Journal: Development
Development (2021) 148 (18): dev198960.
Published: 29 March 2021
... cell movement at the leading edge mesendoderm surface allows this tissue to move by being pulled forward by cells at its front end. Xenopus X-ray tomography Gastrulation Cell migration Surface tension Mass cell migration positions organ rudiments during development. In the Xenopus...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (5): dev196949.
Published: 5 March 2021
..., consistent with its migration arrest being temporally regulated, its final position is sensitive to body size. Cell migration Neuroblast Robustness Body size C. elegans Human Frontier Science Program http://dx.doi.org/10.13039/100004412 RGP0030/2016 Cell migration is a key...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev186999.
Published: 17 June 2020
... in the mouse. This collective cell migration is preceded by a columnar-to-squamous transition in visceral endoderm cells that depends on MLL4. Furthermore, Mll4 mutants display incompletely penetrant, sex-distorted, embryonic haploinsufficiency and adult heterozygous mutants show aspects of Kabuki syndrome...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (23): dev172056.
Published: 5 December 2019
...Abhinava K. Mishra; Joseph P. Campanale; James A. Mondo; Denise J. Montell ABSTRACT Collective cell migration is the coordinated movement of a physically connected group of cells and is a prominent driver of development and metastasis. Interactions between cells within migrating collectives...
Journal Articles
Journal: Development
Development (2019) 146 (10): dev168427.
Published: 15 May 2019
... the importance of cholesterol modification in the processing and long-distance transmission of the Hh ligand, we have analyzed the involvement of the Niemann-Pick disease type C-1a (NPC1a) protein, a cholesterol transporter, in germ cell migration and Hedgehog signaling. We show that mesoderm-specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev165852.
Published: 21 November 2018
... overlying the extra-embryonic ectoderm shows coherent cell growth in a proximal-anterior to distal-posterior direction. We also observed that directional cell migration is coupled with cell elongation in the anterior region. Our observations suggest that the behaviors of visceral endoderm cells vary between...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (22): dev164269.
Published: 21 November 2018
..., and a constitutively active form of Src efficiently rescues the Gα13 morphant phenotype in NC cells. We propose that Ric-8A-mediated Gα13 signalling is required for proper cranial NC cell migration by regulating focal adhesion dynamics and protrusion formation. Cells were harvested in lysis buffer [0.5% IGEPAL...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev163303.
Published: 28 August 2018
... and compiled using Adobe Photoshop and Adobe Illustrator software. Cell tracking was analyzed using the manual tracking plug-in of the Fiji software. Data were exported to Microsoft Excel and the speed, path and direction of cell migration were determined as previously reported ( Lin et al., 2005 ; Ye and Lin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (14): dev161117.
Published: 30 July 2018
... and to specifically decipher the mechanisms controlling collective cell migration. Here, we identify the Drosophila Insulin/Insulin-like growth factor signalling (IIS) pathway as a key regulator in controlling actin dynamics in border cells, independently of its function in growth control. Loss of IIS activity blocks...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev161182.
Published: 2 July 2018
... that Cdc42 is required for endothelial tip cell selection, directed cell migration and filopodia formation, but dispensable for cell proliferation or apoptosis. Although the loss of Cdc42 seems generally compatible with apical-basal polarization and lumen formation in retinal blood vessels, it leads...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3241–3252.
Published: 15 September 2017
... mechanical stimulation. SMAD signaling Coronary artery Shear stress Endothelial cells Cell migration Mechanical signals are an integral component of tissue development and homeostasis, in which they can influence cell behavior by inducing structural and transcriptional changes. However, we...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (17): 3102–3113.
Published: 1 September 2017
...James B. Skeath; Beth A. Wilson; Selena E. Romero; Mark J. Snee; Yi Zhu; Haluk Lacin The extracellular matrix (ECM) regulates cell migration and sculpts organ shape. AdamTS proteins are extracellular metalloproteases known to modify ECM proteins and promote cell migration, but demonstrated roles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2961–2968.
Published: 15 August 2017
... that, despite the depletion of MyoII function, tip cell migration and stalk cell intercalation (SCI) proceed at a normal rate. This confirms a model in which DB elongation and SCI in the trachea occur as a consequence of tip cell migration, which produces the necessary forces for the branching process...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (11): 2045–2058.
Published: 1 June 2017
..., high COUP-TFI expression levels downregulate Cxcr4 expression, whereas increased Cxcr4 expression in wild-type hippocampal cells affects cell migration. Finally, loss of COUP-TFI in postmitotic cells leads to only minor and transient abnormalities, and to normal Cxcr4 expression. Together, our results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 187–200.
Published: 15 January 2017
...Crystal F. Davey; Cecilia B. Moens ABSTRACT The planar cell polarity (PCP) pathway is best known for its role in polarizing epithelial cells within the plane of a tissue but it also plays a role in a range of cell migration events during development. The mechanism by which the PCP pathway polarizes...