1-20 of 140
Keywords: Cell migration
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200001.
Published: 2 December 2021
..., leading to increased speed of migration. Moreover, overactivation of Rac1, due to Piezo1 inhibition, counteracts cell migration inhibitory signals by Semaphorin 3A and Semaphorin 3F, generating aberrant neural crest invasion in vivo . Thus, we find that, for directional migration in vivo , neural crest...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (7): dev191767.
Published: 1 April 2021
...Jessica Stock; Andrea Pauli ABSTRACT Self-organization is a key feature of many biological and developmental processes, including cell migration. Although cell migration has traditionally been viewed as a biological response to extrinsic signals, advances within the past two decades have...
Journal Articles
Journal: Development
Development (2021) 148 (18): dev198960.
Published: 29 March 2021
... cell movement at the leading edge mesendoderm surface allows this tissue to move by being pulled forward by cells at its front end. Xenopus X-ray tomography Gastrulation Cell migration Surface tension Mass cell migration positions organ rudiments during development. In the Xenopus...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (5): dev196949.
Published: 5 March 2021
...) exhibited several defects, including cell migration defects for BDU, ALM and/or dorsal-ventral migration of QR.paa and QR.pap; glo-1(zu391) mutants had long eggs but small and sick larvae. We then compared QR.pax final position of the mutants to N2 with a two-sided t -test and P -values were adjusted...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev186999.
Published: 17 June 2020
... in the mouse. This collective cell migration is preceded by a columnar-to-squamous transition in visceral endoderm cells that depends on MLL4. Furthermore, Mll4 mutants display incompletely penetrant, sex-distorted, embryonic haploinsufficiency and adult heterozygous mutants show aspects of Kabuki syndrome...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (23): dev172056.
Published: 5 December 2019
...Abhinava K. Mishra; Joseph P. Campanale; James A. Mondo; Denise J. Montell ABSTRACT Collective cell migration is the coordinated movement of a physically connected group of cells and is a prominent driver of development and metastasis. Interactions between cells within migrating collectives...
Journal Articles
Journal: Development
Development (2019) 146 (10): dev168427.
Published: 15 May 2019
... the importance of cholesterol modification in the processing and long-distance transmission of the Hh ligand, we have analyzed the involvement of the Niemann-Pick disease type C-1a (NPC1a) protein, a cholesterol transporter, in germ cell migration and Hedgehog signaling. We show that mesoderm-specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev164269.
Published: 21 November 2018
..., and a constitutively active form of Src efficiently rescues the Gα13 morphant phenotype in NC cells. We propose that Ric-8A-mediated Gα13 signalling is required for proper cranial NC cell migration by regulating focal adhesion dynamics and protrusion formation. Considering that migrating cranial NC cells express...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev165852.
Published: 21 November 2018
... overlying the extra-embryonic ectoderm shows coherent cell growth in a proximal-anterior to distal-posterior direction. We also observed that directional cell migration is coupled with cell elongation in the anterior region. Our observations suggest that the behaviors of visceral endoderm cells vary between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev163303.
Published: 28 August 2018
... to limit extracellular matrix deposition, creating an environment conducive to this migration. Glypican 4 Endoderm Cell migration Imaging Extracellular matrix The endoderm, the deepest germ layer, contributes to the development of the digestive system, heart and craniofacial structures...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (14): dev161117.
Published: 30 July 2018
... and to specifically decipher the mechanisms controlling collective cell migration. Here, we identify the Drosophila Insulin/Insulin-like growth factor signalling (IIS) pathway as a key regulator in controlling actin dynamics in border cells, independently of its function in growth control. Loss of IIS activity blocks...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev161182.
Published: 2 July 2018
... that Cdc42 is required for endothelial tip cell selection, directed cell migration and filopodia formation, but dispensable for cell proliferation or apoptosis. Although the loss of Cdc42 seems generally compatible with apical-basal polarization and lumen formation in retinal blood vessels, it leads...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3241–3252.
Published: 15 September 2017
... induced by blood flow. Highlighted Article: BMP/SMAD signaling is required for endothelial cells to align and migrate in a directional manner in response to blood flow-induced mechanical stimulation. SMAD signaling Coronary artery Shear stress Endothelial cells Cell migration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (17): 3102–3113.
Published: 1 September 2017
...James B. Skeath; Beth A. Wilson; Selena E. Romero; Mark J. Snee; Yi Zhu; Haluk Lacin The extracellular matrix (ECM) regulates cell migration and sculpts organ shape. AdamTS proteins are extracellular metalloproteases known to modify ECM proteins and promote cell migration, but demonstrated roles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2961–2968.
Published: 15 August 2017
... that, despite the depletion of MyoII function, tip cell migration and stalk cell intercalation (SCI) proceed at a normal rate. This confirms a model in which DB elongation and SCI in the trachea occur as a consequence of tip cell migration, which produces the necessary forces for the branching process...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (11): 2045–2058.
Published: 1 June 2017
..., high COUP-TFI expression levels downregulate Cxcr4 expression, whereas increased Cxcr4 expression in wild-type hippocampal cells affects cell migration. Finally, loss of COUP-TFI in postmitotic cells leads to only minor and transient abnormalities, and to normal Cxcr4 expression. Together, our results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 187–200.
Published: 15 January 2017
...Crystal F. Davey; Cecilia B. Moens ABSTRACT The planar cell polarity (PCP) pathway is best known for its role in polarizing epithelial cells within the plane of a tissue but it also plays a role in a range of cell migration events during development. The mechanism by which the PCP pathway polarizes...
Journal Articles
Journal: Development
Development (2016) 143 (22): 4261–4271.
Published: 15 November 2016
...-induced expression of the transcription factor Escargot, which subsequently suppresses ERK signaling. Tubulogenesis Tip cell Cell migration FGF signaling ERK signaling Tubular organs allow for circulation through blood vessels and promote the exchange of gases in the mammalian lung...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (17): 3206–3215.
Published: 1 September 2016
...Vincent Stepanik; Leslie Dunipace; Young-Kyung Bae; Frank Macabenta; Jingjing Sun; Nathanie Trisnadi; Angelike Stathopoulos Caudal visceral mesoderm (CVM) cells migrate from posterior to anterior of the Drosophila embryo as two bilateral streams of cells to support the specification of longitudinal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1512–1522.
Published: 1 May 2016
... implicated in cell migration [ Prokr2 (prokineticin receptor 2), Nrp2 (neuropilin 2), Cd74 (HLA class II histocompatibility antigen gamma chain or HLA-DR antigen-associated invariant chain; which can act as a receptor for macrophage migration inhibitory factor)] or are involved in cell-adhesion...
Includes: Supplementary data