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Keywords: Cell death
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev199750.
Published: 14 October 2021
... Forger , N. G. and de Vries , G. J. ( 2010 ). Cell death and sexual differentiation of behavior: worms, flies, and mammals . Curr. Opin. Neurobiol. 20 , 776 - 783 . 10.1016/j.conb.2010.09.006 Franco , H. L. and Yao , H. H.-C. ( 2012 ). Sex and hedgehog: roles of genes...
Journal Articles
Journal: Development
Development (2021) 148 (14): dev198705.
Published: 27 July 2021
... were caused by JNK-mediated cell death in the wing pouch via Eiger/TNF signaling. The JNK activation in M /+, yki /+ wing discs required the caspase Dronc, which is normally blocked by DIAP1. Notably, heterozygosity of yki reduced DIAP1 expression in the wing pouch, leading to elevation of Dronc...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev191882.
Published: 24 July 2020
...Piya Ghose; Shai Shaham ABSTRACT Cell death is an important facet of animal development. In some developing tissues, death is the ultimate fate of over 80% of generated cells. Although recent studies have delineated a bewildering number of cell death mechanisms, most have only been observed...
Journal Articles
Journal: Development
Development (2018) 145 (9): dev156018.
Published: 25 April 2018
... , L. ( 2015 ). Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila . Open Biol.   5 , 140171 . 10.1098/rsob.140171 Yu , L. , Wang , L. and Chen , S. ( 2010 ). Endogenous toll-like receptor ligands and their biological significance . J. Cell. Mol. Med...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (8): dev152041.
Published: 18 April 2018
... Asymmetrical divisions Cell death In silico experimentation 3D+time 2-photon imaging Variability coincides with the possibility of adapting to changing environments ( Darwin, 1859 ). Consistently, wild-type populations are intrinsically variable ( Raj and van Oudenaarden, 2008 ). The production...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (8): 1566–1577.
Published: 15 April 2017
.... Ikaros Neurogenesis Medium spiny neurons Cell cycle Cell death Ikzf2 The mammalian striatum controls body movements through a sophisticated neuronal network that is dependent on the neurogenesis of two major classes of striatal neurons: the striatal projection neurons (or medium spiny...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (18): 3300–3305.
Published: 15 September 2016
... within the maternally derived seed coat. In Arabidopsis , final seed size is determined by early expansion of the coenocytic endosperm, which then cellularises and subsequently undergoes developmental programmed cell death, breaking down as the embryo grows. Endosperm breakdown requires the endosperm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (15): 2780–2790.
Published: 01 August 2016
... . 10.1073/pnas.94.8.4223 Christensen , C. A. , Gorsich , S. W. , Brown , R. H. , Jones , L. G. , Brown , J. , Shaw , J. M. and Drews , G. N. ( 2002 ). Mitochondrial GFA2 is required for synergid cell death in Arabidopsis . Plant Cell   14 , 2215 - 2232 . 10.1105/tpc...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1560–1570.
Published: 01 May 2016
...Amanda B. Wehner; Houari Abdesselem; Travis L. Dickendesher; Fumiyasu Imai; Yutaka Yoshida; Roman J. Giger; Brian A. Pierchala ABSTRACT During development of the peripheral nervous system, excess neurons are generated, most of which will be lost by programmed cell death due to a limited supply...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (4): 763–773.
Published: 15 February 2015
... mutant in which the jag1b gene is disrupted by an EGFP insertion. Loss of Jag1b causes cell death in the developing posterior crista and results in downregulation of fgf10a in the posterior prosensory cells. Inhibition of FGFR activity in wild-type embryos also causes loss of the posterior crista...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 770–779.
Published: 15 February 2013
... ( Tsuwamoto et al., 2008 ). Cell death cuticle Embryo Endosperm Seed development Signalling Seed production in angiosperms requires a tight coordination of the development of the two zygotic products of double fertilization: the embryo and the endosperm. In the model species Arabidopsis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (21): 4029–4039.
Published: 01 November 2012
... cells, and activates the JNK pathway. Overexpression of Draper or the JNK pathway in follicle cells is sufficient to induce death of the underlying germline, suggesting that there is coordination between the germline and follicular epithelium to promote germline cell death. Furthermore, activation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (1): 107–116.
Published: 01 January 2012
..., when diluted in high DMSO concentrations, causes enhanced cell death in the wound epidermis and blastema ( Géraudie and Ferretti, 1997 ). We have developed an RA treatment regime that does not induce cell death; rather, it demonstrably enhances RA signaling and positively influences fin regeneration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (10): 2003–2014.
Published: 15 May 2011
...Lukas Jakob Neukomm; Anne-Sophie Nicot; Jason Michael Kinchen; Johann Almendinger; Sérgio Morgado Pinto; Sheng Zeng; Kimon Doukoumetzidis; Hélène Tronchère; Bernard Payrastre; Jocelyn Franck Laporte; Michael Otmar Hengartner Multicellular organisms use programmed cell death to eliminate unwanted...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3433–3442.
Published: 15 October 2009
... control of neuronal numbers is achieved during neural development is largely unclear. Specifically, the role of programmed cell death in control of cell numbers has not been studied in the central brain neuroblast lineages. Here, we focus on four postembryonic neuroblast lineages in the central brain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 275–283.
Published: 15 January 2009
...Kathleen A. Galindo; Wan-Jin Lu; Jae H. Park; John M. Abrams Bcl-2 family members are pivotal regulators of programmed cell death (PCD). In mammals, pro-apoptotic Bcl-2 family members initiate early apoptotic signals by causing the release of cytochrome c from the mitochondria, a step necessary...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2573–2582.
Published: 01 August 2008
... wall patterning. This was further supported by our observations that the vessel elements of acl5 seemed to initiate the cell death program too early and that the xylem defects associated with acl5 could be largely phenocopied by induction of premature, diphtheria toxin-mediated cell death in the ACL5...
Journal Articles
Journal: Development
Development (2007) 134 (2): 367–379.
Published: 15 January 2007
... 2 11 2006 © 2007. 2007 Drosophila Metamorphosis Histoblasts Morphogenesis Abdomen Cell death Cell replacement One of the main processes leading to the shaping of the three-dimensional body plan of higher organisms is the dynamic rearrangement of cell populations...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4771–4781.
Published: 01 December 2006
...Amit Singh; Xiao Shi; Kwang-Wook Choi Organogenesis involves an initial surge of cell proliferation, leading to differentiation. This is followed by cell death in order to remove extra cells. During early development, there is little or no cell death. However,there is a lack of information...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (24): 5343–5352.
Published: 15 December 2005
...Christian Werz; Tom V. Lee; Peter L. Lee; Melinda Lackey; Clare Bolduc; David S. Stein; Andreas Bergmann Incorrectly specified or mis-specified cells often undergo cell death or are transformed to adopt a different cell fate during development. The underlying cause for this distinction is largely...
Includes: Supplementary data