...Olivia R. A. Tidswell; Matthew A. Benton; Michael Akam ABSTRACT The neuroblast timer genes hunchback , Krüppel , nubbin and castor are expressed in temporal sequence in neural stem cells, and in corresponding spatial sequence along the Drosophila blastoderm. As canonical gap genes, hunchback...

... , J. , Estacio-Gomez , A. , Moris-Sanz , M. , Baumgardt , M. , Thor , S. and Diaz-Benjumea , F. J. ( 2010 ). A genetic cascade involving klumpfuss, nab and castor specifies the abdominal leucokinergic neurons in the Drosophila CNS . Development   137 , 3327 - 3336 . 10.1242...

... to understanding the process of cardiac development and the pathology associated with human congenital heart disease. Here, we show that the cardiac transcription factor CASTOR (CASZ1) directly interacts with congenital heart disease 5 protein (CHD5), which is also known as tryptophan-rich basic protein (WRB...

...Khoa D. Tran; Chris Q. Doe Neurogenesis in Drosophila and mammals requires the precise integration of spatial and temporal cues. In Drosophila , embryonic neural progenitors (neuroblasts) sequentially express the transcription factors Hunchback, Kruppel, Pdm1/Pdm2 (Pdm) and Castor as they generate...