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Keywords: Cardiac fusion
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Journal Articles
Journal: Development
Development (2016) 143 (16): 2965–2972.
Published: 15 August 2016
... of Tmem2 can rescue the MZtmem2 mutant phenotype. Injection of wild-type tmem2 mRNA into MZtmem2 mutants can rescue both muscle fiber attachment ( Fig. 1 I,L; Table S1 ) and cardiac fusion ( Fig. 3 F-K; Table S2 ). Similarly, we found that the Tmem2 ectodomain can also ameliorate both...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (19): 4199–4205.
Published: 1 October 2011
... to the midline normally, indicating that frv facilitates cardiac fusion. Positional cloning reveals that the frv locus encodes Tmem2, a predicted type II single-pass transmembrane protein. Homologs of Tmem2 are present in all examined vertebrate genomes, but nothing is known about its molecular or cellular...
Includes: Supplementary data