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Keywords: Caenorhabditis elegans
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (1): dev201366.
Published: 3 January 2023
... the entire Caenorhabditis elegans nervous system. Distinct, lineage-specific proneural class II bHLH factors are generally thought to operate via interaction with a common, class I bHLH subunit, encoded by Daughterless in flies, the E proteins in vertebrates and HLH-2 in C. elegans . To eliminate function...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2022) 149 (10): dev200229.
Published: 30 May 2022
...Rudra Prasanna Banerjee; Martin Srayko ABSTRACT In most sexually reproducing animals, sperm entry provides the signal to initiate the final stages of female meiosis. In Caenorhabditis elegans , this signal is required for completion of female anaphase I and entry into meiosis II (MII). memi - 1/2/3...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (9): dev200401.
Published: 12 May 2022
... in a manner dependent on the local contour and other factors. The prediction was validated experimentally by increasing the extra-embryonic space in the Caenorhabditis elegans embryo. Overall, our analyses characterized the roles of geometrical contributors, specifically the amount of extra-embryonic space...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (1): dev199900.
Published: 4 January 2022
...Silvan Spiri; Simon Berger; Louisa Mereu; Andrew DeMello; Alex Hajnal ABSTRACT During Caenorhabditis elegans vulval development, the uterine anchor cell (AC) first secretes an epidermal growth factor (EGF) to specify the vulval cell fates and then invades the underlying vulval epithelium. By doing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (20): dev193995.
Published: 22 October 2021
... regulated is less understood. Here, we report a mechanism controlling tail-spike cell death onset during Caenorhabditis elegans development. We show that the zinc-finger transcription factor BLMP-1, which controls larval development timing, also regulates embryonic tail-spike cell death initiation. BLMP-1...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (11): dev198044.
Published: 10 June 2021
... the initial response to axonal injury has been studied in great detail, it is rather unclear what controls the re-establishment of a functional connection. Using the posterior lateral microtubule neuron in Caenorhabditis elegans , we found that after axotomy, the regrowth from the proximal stump towards...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (5): dev194167.
Published: 5 March 2021
...Kimberley D. Gauthier; Christian E. Rocheleau ABSTRACT The evolutionarily conserved LIN-2 (CASK)/LIN-7 (Lin7A-C)/LIN-10 (APBA1) complex plays an important role in regulating spatial organization of membrane proteins and signaling components. In Caenorhabditis elegans , the complex is essential...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (5): dev195875.
Published: 5 March 2021
... is identified as an essential factor for C. elegans spermatogenesis, functioning with the kinase SPE-6 to sequester the cytoskeletal element MSP into fibrous bodies. Major sperm protein Intrinsically disordered protein Caenorhabditis elegans Spermatogenesis Cytoskeletal assembly spe-18...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (3): dev196600.
Published: 10 February 2021
.... In Caenorhabditis elegans , this reprogramming is mediated by the H3K4me2 demethylase SPR-5 and the H3K9 methyltransferase, MET-2. In contrast, the H3K36 methyltransferase MES-4 maintains H3K36me2/3 at germline genes between generations to facilitate re-establishment of the germline. To determine whether the MES-4...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (20): dev193805.
Published: 26 October 2020
... is poorly understood. The Caenorhabditis elegans SMD motor neurons terminate axon outgrowth upon sexual maturity and partially retract their axons during early adulthood. Here we show that C-terminal binding protein 1 (CTBP-1), a transcriptional corepressor, is required for correct SMD axonal development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev188011.
Published: 22 July 2020
... a conformational switch from an inactive cytoplasmic form into an active membrane- and actin-bound form, which is thought to be mediated by sequential PIP 2 binding and phosphorylation of a conserved C-terminal threonine residue. Here, we use the single Caenorhabditis elegans ERM ortholog, ERM-1, to study...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (18): dev180059.
Published: 25 September 2019
...Annabel Ebbing; Teije C. Middelkoop; Marco C. Betist; Eduard Bodewes; Hendrik C. Korswagen ABSTRACT Directional migration of neurons and neuronal precursor cells is a central process in nervous system development. In the nematode Caenorhabditis elegans , the two Q neuroblasts polarize and migrate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (5): dev172031.
Published: 4 March 2019
... differentiation. In Caenorhabditis elegans and other animals, the RNA-binding protein LIN-28 post-transcriptionally inhibits let-7 biogenesis at early developmental stages, but the mechanisms by which LIN-28 does this are not fully understood. Nor is it understood how the developmental regulation of let-7 might...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev169482.
Published: 23 January 2019
... and positioned below the microvillar brush border, which suggests a protective intracellular barrier function. To test this, we used Caenorhabditis elegans , the intestinal cells of which are endowed with a particularly dense intermediate filament-rich layer that is referred to as the endotube. We found...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (24): dev167734.
Published: 18 December 2018
... post-meiotic maturation en route to the oocyte. This is regulated largely by soma-derived cues. In Caenorhabditis elegans , this process is called sperm activation, and it transforms immotile spermatids into migratory fertilization-competent cells. Here, we show that the negative regulator of sperm...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (7): dev163949.
Published: 29 March 2018
... cells of the germline. Germ cells Meiosis Caenorhabditis elegans pas-1 rpn-1 htp-3 Sexual reproduction depends on the formation of haploid gametes from diploid parent cells. This reduction in ploidy requires accurate segregation of homologous chromosomes (homologs...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (18): 3253–3263.
Published: 15 September 2017
... microscopy to elucidate and compare the intermediate steps of RB formation in Caenorhabditis elegans , Rhabditis sp. SB347 (recently named Auanema rhodensis ) and related nematodes. In all cases, intact microtubules reorganize and move from centrosomal to non-centrosomal sites at the RB-sperm boundary...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2364–2374.
Published: 1 July 2017
... expression of the fusion protein AFF-1. Thus, ectopic expression of the fusogen AFF-1 in the PVD and mutations in daf-2 differentially rejuvenate some aspects of dendritic regeneration following injury. AFF-1 Dendritic remodeling Caenorhabditis elegans Regeneration by self-fusion EFF-1 Neuronal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (14): 2464–2477.
Published: 15 July 2015
... in other organisms, SoxB and SoxC genes in C. elegans have no broad function in embryonic nervous system development; instead, SoxB genes control the terminal differentiation of restricted neuron types. Caenorhabditis elegans Sox genes Neurogenesis Comparing the function of specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 291–302.
Published: 15 January 2015
... the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes . Mol. Cell. Biol.   19 , 1479 - 1485 . Brenner , S. ( 1974 ). The genetics of Caenorhabditis elegans . Genetics   77 , 71 - 94 . Buckley , S. M. , Aranda-Orgilles , B...
Includes: Supplementary data