...). The nuclear architectural proteins cohesin and CCCTC-binding factor (CTCF) contribute to chromatin structure and gene regulation. We show here that normal cohesin function is important for ZGA in zebrafish. Depletion of the cohesin subunit Rad21 delays ZGA without affecting cell cycle progression. In contrast...

... nervous system and how such diversity may be used in neural circuit assembly. * Author for correspondence ( tm2472@columbia.edu ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 CTCF...

... financial interests. 29 6 2011 © 2011. Chromatin insulator Gene loop Insulator-promoter interaction CTCF Su(Hw) Drosophila Insulators regulate gene activity in a variety of organisms. The defining feature of insulators as a class of regulatory elements...

...Le-Ben Wan; Hua Pan; Sridhar Hannenhalli; Yong Cheng; Jun Ma; Andrew Fedoriw; Victor Lobanenkov; Keith E. Latham; Richard M. Schultz; Marisa S. Bartolomei CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery...