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Keywords: C3G
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Journal Articles
Journal: Development
Development (2003) 130 (2): 355–367.
Published: 15 January 2003
...Anne K. Voss; Peter Gruss; Tim Thomas The Ras signalling pathway has major roles in normal cell function and oncogenesis. C3G is a guanine nucleotide exchange factor for members of the Ras family of GTPases. We generated a mouse strain with a hypomorphic C3G allele. C3G gt/gt mutant embryos died...