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In collection:Reproductive biology
Kelsey E. Brooks, Brittany L. Daughtry, Brett Davis, Melissa Y. Yan, Suzanne S. Fei, Selma Shepherd, Lucia Carbone, Shawn L. Chavez
Development (2022) 149 (7): dev198341.
Published: 14 April 2022
... was also revealed, and single-cell DNA-seq showed propagation of primarily non-reciprocal mitotic errors. Depletion of the mitotic checkpoint protein BUB1B (also known as BUBR1) resulted in similarly abnormal nuclear structures and cell divisions, as well as chaotic aneuploidy and dysregulation...
Includes: Supplementary data
Development (2005) 132 (20): 4509–4520.
Published: 15 October 2005
... that the conserved spindle checkpoint protein BubR1 is required during early embryonic development. BubR1 is maternally provided and localises to kinetochores from prophase to metaphase during syncytial divisions similarly to somatic cells. To determine BubR1 function during embryogenesis, we generated a new...
Includes: Multimedia, Supplementary data