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Keywords: Brain development
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (18): dev200616.
Published: 26 September 2022
... , C. A. , Wenzel , D. , Bicknell , L. S. , Hurles , M. E. , Homfray , T. , Penninger , J. M. , Jackson , A. P. and Knoblich , J. A. ( 2013 ). Cerebral organoids model human brain development and microcephaly . Nature 501 , 373 - 379 . 10.1038/nature12517...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (8): dev200425.
Published: 3 May 2022
... of the brain. Apart from being highly specialized brain phagocytes, microglia modulate the development and functions of neurons and glial cells through both direct and indirect interactions. Thus, recognizing the elements that influence the homeostasis and heterogeneity of microglia in normal brain development...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (7): dev199987.
Published: 31 March 2022
... 2021 28 2 2022 © 2022. Published by The Company of Biologists Ltd 2022 Summary: Analysis of the effect on brain development of mutations in the Drosophila traip gene reveals that Traip suppresses DNA bridges and premature neural stem cell loss to ensure proper brain size...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (5): dev199985.
Published: 7 March 2022
...Jiancheng Liu; Xiwei Wu; Qiang Lu ABSTRACT During mammalian brain development, how different astrocytes are specified from progenitor cells is not well understood. In particular, whether astrocyte progenitor cells (APCs) start as a relatively homogenous population or whether there is early...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (17): dev199417.
Published: 9 September 2021
...Nereo Kalebic; Takashi Namba ABSTRACT Cell polarity is fundamentally important for understanding brain development. Here, we hypothesize that the inheritance and flexibility of cell polarity during neocortex development could be implicated in neocortical evolutionary expansion. Molecular...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (16): dev190181.
Published: 25 August 2020
... of crucial thalamic electrophysiological features. TCF7L2 Thalamus Brain development Neuronal identity Terminal selector Transcription factor Studies of invertebrates have shown that terminal differentiation gene batteries in individual classes of neurons are induced and maintained...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (20): dev174318.
Published: 11 October 2019
... in clinically observed congenital malformations. Future studies are warranted to elucidate the relative contributions of these factors in brain development. At later stages of hemisphere morphogenesis, mesenchyme between the cortical hemispheres has been proposed as a crucial factor in roof plate signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (18): dev181933.
Published: 18 September 2019
... of this strain demonstrates that p75 NTR regulates multiple aspects of brain development, including cortical progenitor cell survival, and that expression during early neurogenesis is required for appropriate formation of telencephalic structures. As the functional outcome of p75 NTR signaling is highly...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (1): dev154500.
Published: 9 January 2018
.... Collectively, our data provide the first evidence for involvement of Ccdc39 in hydrocephalus and suggest that the proper development of medial wall ependymal cilia is crucial for normal mouse brain development. * Authors for correspondence ( Rolf.Stottmann@cchmc.org ; June.Goto@cchmc.org ) Competing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev160051.
Published: 8 January 2018
... Neurogenesis Brain development Behavior Evolution Pleurodeles Notophthalmus Newt Brain ontogeny follows an evolutionarily conserved order among vertebrates but there is a considerable diversity of brain anatomy among different species ( Charvet et al., 2011 ; Medina and Abellan, 2009...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (21): 3932–3945.
Published: 1 November 2017
...) lineage formation. We show that Barc is required for the generation of neurons during Drosophila brain development by ensuring correct neural progenitor proliferation and differentiation. Barc associates with components of the U2 small nuclear ribonucleoprotein (snRNP) complex, and its depletion causes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1616–1627.
Published: 1 May 2015
...Mei Yang; Si-Lu Yang; Stephanie Herrlinger; Chen Liang; Monika Dzieciatkowska; Kirk C. Hansen; Ridham Desai; Andras Nagy; Lee Niswander; Eric G. Moss; Jian-Fu Chen Neural progenitor cells (NPCs) have distinct proliferation capacities at different stages of brain development. Lin28 is an RNA-binding...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3793–3798.
Published: 1 October 2014
... & Sons Inc . © 2014. Published by The Company of Biologists Ltd 2014 Atomic force microscopy Elasticity Mechanical property Embryonic tissue Brain development Cerebral cortex Mechanotransduction Neural stem cells Mouse During development, somatic stem cells define specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 11–16.
Published: 1 January 2014
... approaches available to study brain development and evolution is impressive, but overall, the meeting identified our ignorance of human-specific traits. We must channel these diverse approaches to study human brain development and resolve fundamental questions related to human uniqueness. As Voltaire said...
Journal Articles
Journal: Development
Development (2013) 140 (13): 2818–2822.
Published: 1 July 2013
... ( federico.calegari@crt-dresden.de ) Competing interests statement The authors declare no competing financial interests. 23 4 2013 © 2013. Published by The Company of Biologists Ltd 2013 Lentiviral injection Brain development Gene expression Cre recombination...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (6): 1250–1261.
Published: 15 March 2013
... the developing vertebrate central nervous system. However, its conditional deletion at E12.5 in mouse causes few brain developmental problems, with the exception of the postnatal loss of the hippocampal radial glia stem cells and the dentate gyrus. We deleted Sox2 at E9.5 in the telencephalon, using a Bf1-Cre...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2510–2522.
Published: 15 July 2012
.... ( 2008 ). Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development . Neural Dev. 3 , 5 . Bossing T. , Technau G. M. ( 1994 ). The fate of the CNS midline progenitors in Drosophila as revealed by a new method for single cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (23): 3937–3947.
Published: 1 December 2009
...: tailless regulates expression of empty spiracles in early embryonic patterning and brain development . Mech. Dev. 109 , 161 - 172 . Hirth F. , Therianos S. , Loop T. , Gehring W. J. , Reichert H. , Furukubo-Tokunaga K. ( 1995 ). Developmental defects in brain...
Journal Articles
Journal: Development
Development (2007) 134 (17): 3089–3097.
Published: 1 September 2007
...Nicola Grillenzoni; Adrien Flandre; Christelle Lasbleiz; Jean-Maurice Dura In recent decades, Drosophila mushroom bodies (MBs) have become a powerful model for elucidating the molecular mechanisms underlying brain development and function. We have previously characterized the derailed ( drl ; also...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1291–1300.
Published: 1 April 2007
..., H. ( 1998 ). Homeotic gene action in embryonic brain development of Drosophila. Development 125 , 1579 -1589. Hirth, F., Kammermeier, L., Frei, E., Walldorf, U., Noll, M. and Reichert, H. ( 2003 ). An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila...