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Development (2008) 135 (15): 2637–2648.
Published: 1 August 2008
... loss causes neuromuscular junction (NMJ) synapse over-elaboration (overgrowth,overbranching, excess synaptic boutons), accumulation of development-arrested satellite boutons, and altered neurotransmission. We used the Gene-Switch method to conditionally drive dFMRP expression to define...
Development (2006) 133 (23): 4655–4665.
Published: 1 December 2006
... (NMJ). At the NMJ, we find that rab11 is important for synaptic morphogenesis, as reductions in rab11 function cause increases in bouton density and branching. These defects are also suppressed by loss of bchs . Taken together, these data identify Bchs as an antagonist of Rab11 during development...