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Keywords: Beta cell
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Journal Articles
Journal: Development
Development (2015) 142 (8): 1407–1417.
Published: 15 April 2015
... of contextual regulators of cell fate acquisition and maintenance. In murine models of diabetes, glucagon-secreting alpha cells transdifferentiate into insulin-secreting beta cells following targeted beta cell depletion, regenerating the form and function of the pancreatic islet. However, the molecular triggers...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (5): 858–870.
Published: 1 March 2015
... in humans, causes pancreatic endocrine differentiation defects leading to cyst formation. Embryo Pancreas Progenitors Endocrine Beta cell Insulin Diabetes Differentiation RNA-binding protein Cysts MODY5 The pancreas is an endoderm-derived organ with dual functions. Acini have...
Includes: Supplementary data