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Keywords: Basal cellClose
Melinda E. Snitow, Shanru Li, Michael P. Morley, Komal Rathi, Min Min Lu, Rachel S. Kadzik, Kathleen M. Stewart, Edward E. Morrisey
Development (2015) 142 (1): 108–117.
Published: 1 January 2015
... downregulated by late gestation. Deletion of Ezh2 in early lung endoderm progenitors leads to the ectopic and premature appearance of Trp63+ basal cells that extend the entire length of the airway. Loss of Ezh2 also leads to reduced secretory cell differentiation. In their place, morphologically similar cells...
Includes: Supplementary data