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Keywords: BMP pathway
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Journal Articles
Journal: Development
Development (2021) 148 (2): dev189944.
Published: 20 January 2021
... the ventral and dorsal territories. This process relies on a complex interplay between the Nodal and BMP pathways through numerous regulatory circuits. To decipher the interplay between these pathways, we used a combination of treatments with recombinant Nodal and BMP2/4 proteins and a computational modelling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (17): 2915–2925.
Published: 1 September 2010
... by regulation of BMP activity. Our study indicates that expression of Noggin, a BMP extracellular inhibitor, is repressed by H3K27me3. Moreover, we show that Noggin expression is induced by BMP pathway signaling, generating a negative-feedback regulatory loop. In response to BMP pathway activation, JMJD3...
Includes: Supplementary data