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Keywords: Axon
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Journal Articles
Journal: Development
Development (2020) 147 (19): dev191155.
Published: 9 October 2020
... the pruning defects in raw RNAi neurons ( Fig. S5A ), although Fos DN or Jun DN expression was reported to rescue the injury-induced axon degeneration phenotypes in raw mutant motor neurons ( Hao et al., 2019 ). Jun DN or Fos DN expression was able to significantly suppress the puc-LacZ expression...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (3): dev180232.
Published: 3 February 2020
...Cristiano Lucci; Raquel Mesquita-Ribeiro; Alex Rathbone; Federico Dajas-Bailador ABSTRACT Both the establishment of neuronal polarity and axonal growth are crucial steps in the development of the nervous system. The local translation of mRNAs in the axon provides precise regulation of protein...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev172502.
Published: 2 May 2019
...Mary Zakaria; Julien Ferent; Ines Hristovska; Yousra Laouarem; Amina Zahaf; Abdelmoumen Kassoussi; Marie-Eve Mayeur; Olivier Pascual; Frederic Charron; Elisabeth Traiffort ABSTRACT Myelination leads to the formation of myelin sheaths surrounding neuronal axons and is crucial for function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (11): 2153–2169.
Published: 1 June 2011
...Karen Lai Wing Sun; James P. Correia; Timothy E. Kennedy Netrins are secreted proteins that were first identified as guidance cues, directing cell and axon migration during neural development. Subsequent findings have demonstrated that netrins can influence the formation of multiple tissues...
Journal Articles
Journal: Development
Development (2010) 137 (23): 3985–3994.
Published: 1 December 2010
...Seanna M. Martin; Georgeann S. O'Brien; Carlos Portera-Cailliau; Alvaro Sagasti Fragments of injured axons that detach from their cell body break down by the molecularly regulated process of Wallerian degeneration (WD). Although WD resembles local axon degeneration, a common mechanism for refining...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (17): 2955–2964.
Published: 1 September 2009
... of the dynactin complex is essential for the survival of sensory neurons and the maintenance of ganglion cell axons, and functions as a major determinant of apicobasal polarity in retinal radial glia. * Author for correspondence( jarema_malicki@meei.harvard.edu ) 30 6 2009 © 2009. © 2009. 2009...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (7): 1147–1157.
Published: 1 April 2009
...Scott R. Wheeler; Swati Banerjee; Kevin Blauth; Stephen L. Rogers; Manzoor A. Bhat; Stephen T. Crews Glia play crucial roles in ensheathing axons, a process that requires an intricate series of glia-neuron interactions. The membrane-anchored protein Wrapper is present in Drosophila midline glia...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (6): 1189–1199.
Published: 15 March 2008
... in developing chick brain. Prominent binding sites were seen in the olfactory bulb and on retinal axons growing into the optic tectum. Co-precipitation from these tissues and tandem mass spectrometry led to the identification of two associated proteins: contactin 4 and NgCAM. In vitro binding studies revealed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3251–3257.
Published: 15 September 2007
... intraspinal motor axon guidance. In zebrafish sidetracked ( set ) mutants, motor axons exit from the spinal cord at ectopic positions. By single-cell labeling and time-lapse analysis we show that motoneurons with cell bodies adjacent to the segmental exit point properly exit from the spinal cord, whereas...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (11): 2137–2146.
Published: 1 June 2007
.... RGCs with reduced function of Xena/XVASP proteins extended fewer axons out of the eye and possessed dynamic lamellipodial growth cones missing filopodia that advanced slowly in the optic tract. Surprisingly,despite lacking filopodia, the axons navigated along the optic pathway without obvious guidance...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (17): 3329–3340.
Published: 1 September 2006
... Caenorhabditis elegans : the secreted two-Ig domain protein ZIG-4, the FGF receptor EGL-15 and the L1-like SAX-7 protein. These proteins provide crucial information for neuronal structures, such as axons, that allows them to maintain the precise position they acquired during development. Yet, how widespread...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (7): 1713–1726.
Published: 1 April 2005
... is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection. J. Neurochem. 78 , 254 -264. Lundquist, E. A. ( 2003 ). Rac proteins and the control of axon development. Curr. Opin. Neurobiol. 13 , 384 -390. Mattson, M. P., Culmsee, C., Yu, Z. and Camandola, S. ( 2000...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (6): 1203–1213.
Published: 15 March 2003
... screened, yielding defects in neuroblast proliferation, cell size, membrane trafficking, and axon and dendrite morphogenesis. We report mutations that affect these different aspects of morphogenesis and phenotypically characterize a subset. We found that roadblock , which encodes a dynein light chain...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (19): 3773–3782.
Published: 1 October 2001
... ganglion pioneer axons to grow toward their targets have yet to be determined. Here, we show that glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN) constitute target-derived factors for developing ciliary ganglion neurons. Both GDNF and NRTN are secreted from eye muscle located...
Journal Articles
Journal: Development
Development (2000) 127 (4): 703–712.
Published: 15 February 2000
... appropriately to guidance cues presented by other cells or the extracellular matrix, the neuron must express genes to mediate the response. The fax-1 gene of C. elegans is required for pathfinding of axons that extend along the ventral nerve cord. We show that fax-1 is also required for pathfinding of axons...
Journal Articles
Journal: Development
Development (1998) 125 (19): 3853–3863.
Published: 1 October 1998
... initiation. * Author for correspondence (e-mail: a-chiba@uiuc.edu ) 21 07 1998 07 09 1998 © 1998 by Company of Biologists 1998 Adaptin Axon Drosophila Endocytosis Growth cone Internalization Neuromuscular Synaptogenesis Commissureless Initiation...
Journal Articles