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Keywords: Androgen
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Journal Articles
Journal: Development
Development (2005) 132 (15): 3431–3443.
Published: 1 August 2005
... with androgen signaling and controls prostate differentiated response. Here, we show the mouse Foxa1 expression marks the entire embryonic urogenital sinus epithelium (UGE), contrasting with Shh and Foxa2, which are restricted to the basally located cells during prostate budding. The Foxa1-deficient mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (20): 4955–4964.
Published: 15 October 2004
... in the formation of residual cystic structures devoid of epithelium. Therefore, basal cells play critical roles in maintaining ductal integrity and survival of luminal cells. However, regressed p63 –/– prostate did regenerate in response to androgen administration, indicating that basal cells were not essential...