... of young mice. Adult neurogenesis Adult stem cells Quiescence Wnt Francis Crick Institute http://dx.doi.org/10.13039/100010438 Cancer Research UK http://dx.doi.org/10.13039/501100000289 FC0010089 Medical Research Council FC0010089 Wellcome Trust...

...Jarno Drost; Hans Clevers ABSTRACT Adult stem cells from a variety of organs can be expanded long-term in vitro as three-dimensional organotypic structures termed organoids. These adult stem cell-derived organoids retain their organ identity and remain genetically stable over long periods of time...

... other adult stem cells, produce lineage-restricted progenitors and respond to SHH. (A) In the subventricular zone (SVZ) lining the lateral ventricles (LVs), neural stem cells (NSCs; blue) self-renew or divide asymmetrically to generate transit-amplifying cells (TACs, green), progenitors...

... Transcription factor 7-like 1 protein Adult stem cells Lineage tracing Mouse Tcf3 (also known as Tcf7-like 1 or Tcf7l1 ) is a member of the Lef/Tcf family, a group of transcription factors with important roles in development, stem cell homeostasis and malignancy. Tcf3 is a crucial regulator...

...Shrividhya Srinivasan; Anthony P. Mahowald; Margaret T. Fuller The stem cell niche provides a supportive microenvironment to maintain adult stem cells in their undifferentiated state. Adhesion between adult stem cells and niche cells or the local basement membrane ensures retention of stem cells...

...Carolina N. Perdigoto; Francois Schweisguth; Allison J. Bardin Tight regulation of self-renewal and differentiation of adult stem cells ensures that tissues are properly maintained. In the Drosophila intestine, both commitment, i.e. exit from self-renewal, and terminal differentiation...

... ). † Author for correspondence ( roger.patient@imm.ox.ac.uk ) * These authors contributed equally to this work Competing interests statement The authors declare no competing financial interests. 27 5 2011 © 2011. Fgf Nkx2.5 Adult stem cells Haemangioblast Cross...

... populations. * Author for correspondence ( a-dudley@northwestern.edu ) Competing interests statement 15 11 2010 © 2011. CamkII Kinase Growth plate Cartilage Chondrocyte maturation Transit amplification Adult stem cells Chick Mouse During...

...Allison J. Bardin; Carolina N. Perdigoto; Tony D. Southall; Andrea H. Brand; François Schweisguth Adult stem cells maintain tissue homeostasis by controlling the proper balance of stem cell self-renewal and differentiation. The adult midgut of Drosophila contains multipotent intestinal stem cells...

...,and for the origins of stem cells in the adult heart. * Author for correspondence (e-mail: roger.patient@imm.ox.ac.uk ) 24 2 2009 © 2009. 2009 Myelopoiesis Cardiogenesis GATA factors Second heart field Haemangioblasts Transcriptional regulation Evolution Adult stem cells Zebrafish...

...). Scale bar: 50 μm. * Author for correspondence (e-mail: bent.brachvogel@mcri.edu.au ) 22 3 2005 ©2005. 2005 Annexin A5 Perivascular cells Pericytes Adult stem cells Formation of the embryonic vascular system happens before nutrition by diffusion runs into its...