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Keywords: Adherens junctions
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev199831.
Published: 14 October 2021
... be influenced by the size, composition or dynamics of contacts between membranes. The initiation of Notch signalling in the Drosophila embryo occurs during cellularization, when lateral cell membranes and adherens junctions are first being deposited, allowing us to investigate the importance of membrane...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (23): dev193425.
Published: 11 December 2020
... to PCP defects. Tmsb4x depletion did not preclude epidermal cell adhesion in vivo or in vitro ; however, it resulted in abnormal structural organization and stability of adherens junction (AJ) due to defects in filamentous (F)-actin and G-actin distribution. In cultured keratinocytes, TMSB4X depletion...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (7): dev185405.
Published: 06 April 2020
... it occurs via rapid remodeling of adherens junctions or focal adhesion assembly, or both, remains poorly understood. Furthermore, how endothelial cell adhesion is controlled in particular tissues and under different conditions remains unexplored. Here, we have identified an unexpected role...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (20): dev175133.
Published: 02 October 2019
... (WC). To study this, we examined adherens junctions during WC in Drosophila larvae. β-Catenin is reduced at the lateral cell-cell junctions of wound-edge epidermal cells in the early healing stages. Destruction complex components, including Ck1α, GSK3β and β-TrCP, suppress β-catenin levels...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1242–1248.
Published: 01 April 2017
... required for regulation of adherens junction (AJ) stability and dynamics. However, much less is known about how such phosphorylation of E-Cadherin regulates AJ formation and dynamics in vivo . In this report, we generated an extensive array of Drosophila E-Cadherin (DE-Cad) endogenous knock-in alleles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (8): 1492–1501.
Published: 15 April 2015
... retinal organisation and rescues most vav mutant phenotypes. Second, using live imaging in the pupal retina, we observe that vav mutant cells do not form stable adherens junctions, causing various defects, such as recruitment of extra primary pigment cells. In agreement with this role in junction dynamics...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (6): 1102–1112.
Published: 15 March 2015
... pupal lattice, in which hexagonal ommatidial units pack tightly. This process involves the fine regulation of adherens junctions (AJs) and of adhesive E-Cadherin (E-Cad) complexes. Localized accumulation of Bazooka (Baz), the Drosophila PAR3 homolog, has emerged as a critical step to specify where new E...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 363–374.
Published: 15 January 2015
...Pierre-Marie Le Droguen; Sandra Claret; Antoine Guichet; Véronique Brodu Epithelial remodelling is an essential mechanism for organogenesis, during which cells change shape and position while maintaining contact with each other. Adherens junctions (AJs) mediate stable intercellular cohesion...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (15): 3179–3188.
Published: 01 August 2011
... Tight junctions Adherens junctions Interkinetic nuclear migration Midbrain Chick During neurulation, a flat neural plate rolls up to form a closed neural tube. This process involves diverse cell behaviors at specialized regions of the neural plate called hinge points (HPs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 491–501.
Published: 01 February 2007
... ). A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration. Development 131 , 5309 -5317. Duband, J. L., Volberg, T., Sabanay, I., Thiery, J. P. and Geiger, B. ( 1988 ). Spatial and temporal distribution of the adherens-junction-associated adhesion molecule A-CAM...
Journal Articles
Journal: Development
Development (2006) 133 (12): 2407–2418.
Published: 15 June 2006
... both oogenesis and embryonic epithelial integrity ( Cox et al.,1996 ; Tepass et al.,1996 ). In ovaries, loss of APC2 and APC1 had no apparent effect on adhesion, and in embryos we did not observe significant alterations in DE-cadherin or α-catenin localization at adherens junctions. Thus APC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (6): 1101–1112.
Published: 15 March 2006
... ). Adhesion molecules during somitogenesis in the avian embryo. J. Cell Biol. 104 , 1361 -1374. Duband, J. L., Volberg, T., Sabanay, I., Thiery, J. P. and Geiger, B. ( 1988 ). Spatial and temporal distribution of the adherens-junction-associated adhesion molecule A-CAM during avian embryogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (3): 427–437.
Published: 01 February 2003
... localises at adherens junctions of the developing photoreceptor cells. A structure-function analysis of the Mbt protein in vitro and in vivo revealed that the Mbt kinase domain and the GTPase binding domain, which specifically interacts with GTP-loaded Cdc42, are important for Mbt function. Besides...