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Keywords: AML1-ETO
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Journal Articles
Journal: Development
Development (2005) 132 (10): 2263–2272.
Published: 15 May 2005
...Jill Wildonger; Richard S. Mann The human translocation (t8;21) is associated with ∼12% of the cases of acute myelogenous leukemia. Two genes, AML1 and ETO , are fused together at the translocation breakpoint, resulting in the expression of a chimeric protein called AML1-ETO. AML1-ETO is thought...