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Keywords: AER
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Journal Articles
Journal: Development
Development (2014) 141 (21): 4194–4198.
Published: 1 November 2014
...Julia E. VanderMeer; Robin P. Smith; Stacy L. Jones; Nadav Ahituv The limb is widely used as a model developmental system and changes to gene expression patterns in its signaling centers, notably the zone of polarizing activity (ZPA) and the apical ectodermal ridge (AER), are known to cause limb...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (6): 1195–1205.
Published: 15 March 2011
...Jesus C. Casanova; Veronica Uribe; Claudio Badia-Careaga; Giovanna Giovinazzo; Miguel Torres; Juan Jose Sanz-Ezquerro The apical ectodermal ridge (AER) is a specialized epithelium located at the distal edge of the limb bud that directs outgrowth along the proximodistal axis. Although the molecular...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (7): 1219–1229.
Published: 1 April 2006
...Theo P. Hill; Makoto M. Taketo; Walter Birchmeier; Christine Hartmann Recently canonical Wnt signaling in the ectoderm has been shown to be required for maintenance of the apical ectodermal ridge (AER) and for dorsoventral signaling. Using conditional gain- and loss-of-functionβ-catenin alleles, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (17): 4179–4187.
Published: 1 September 2004
.... In the limb, this antagonistic action regulates the formation of the apical ectodermal ridge (AER) in both the mesenchyme and the AER itself, and also controls pattern formation along the proximodistal axis of the limb. Our data introduce a new paradigm of BMP antagonism during limb development mediated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (21): 5103–5111.
Published: 1 November 2003
... Carboxypeptidase Z Somite Sclerotome Pax3 Pax1 Scapula Rib Wnt Cysteine-rich-domain CRD AER Paraxial head mesoderm Chicken Carboxypeptidase Z (CPZ) is a member of the carboxypeptidase E subfamily of metallocarboxypeptidases ( Song and Fricker, 1997 ). Although these Zn-dependent enzymes have...