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Keywords: ADAM
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Journal Articles
Journal: Development
Development (2012) 139 (20): 3693–3709.
Published: 15 October 2012
...Silvio Weber; Paul Saftig Proteolytic enzymes belonging to the A Disintegin And Metalloproteinase (ADAM) family are able to cleave transmembrane proteins close to the cell surface, in a process referred to as ectodomain shedding. Substrates for ADAMs include growth factors, cytokines, chemokines...
Journal Articles
Journal: Development
Development (2010) 137 (14): 2417–2426.
Published: 15 July 2010
.... In a screen for genes involved in Slit-Robo repulsion, we have identified the Adam family metalloprotease Kuzbanian (Kuz). Kuz does not regulate midline repulsion through cleavage of Slit, nor is Slit cleavage essential for repulsion. Instead, Kuz acts in neurons to regulate repulsion and Kuz can cleave...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (14): 3147–3161.
Published: 15 July 2003
...Xun Huang; Peng Huang; Matthew K. Robinson; Michael J. Stern; Yishi Jin The migration of cells and growth cones is a process that is guided by extracellular cues and requires the controlled remodeling of the extracellular matrix along the migratory path. The ADAM proteins are important regulators...
Journal Articles
Journal: Development
Development (2002) 129 (10): 2381–2389.
Published: 15 May 2002
... the ability of ampA null cells to fill this role. Thus, in spite of its simpler structure, the Dictyostelium ampA protein carries out the same diversity of functions that have been observed for the ADAM and ADAMTS families in metazoans. References Abe, T., Early, A., Siegert, F., Weijer, C. and Williams...