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Siew-Lan Ang
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Journal Articles

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells

Emmanouil Metzakopian, Kamal Bouhali, Matías Alvarez-Saavedra, Jeffrey A. Whitsett, David J. Picketts, Siew-Lan Ang
Journal: Development
Development (2015) 142 (7): 1315–1324.
https://doi.org/10.1242/dev.115808
Published: 1 April 2015
View article titled, Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells
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Includes: Supplementary data
Journal Articles

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors

Emmanouil Metzakopian, Wei Lin, Mali Salmon-Divon, Heidi Dvinge, Elisabet Andersson, Johan Ericson, Thomas Perlmann, Jeffrey A. Whitsett, Paul Bertone, Siew-Lan Ang
Journal: Development
Development (2012) 139 (14): 2625–2634.
https://doi.org/10.1242/dev.081034
Published: 15 July 2012
View article titled, Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors
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Includes: Supplementary data
Journal Articles

Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner

Anna L. M. Ferri, Wei Lin, Yannis E. Mavromatakis, Julie C. Wang, Hiroshi Sasaki, Jeffrey A. Whitsett, Siew-Lan Ang
Journal: Development
Development (2007) 134 (15): 2761–2769.
https://doi.org/10.1242/dev.000141
Published: 1 August 2007
View article titled, Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner
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Includes: Supplementary data
Journal Articles

Transcriptional control of midbrain dopaminergic neuron development

Siew-Lan Ang
Journal: Development
Development (2006) 133 (18): 3499–3506.
https://doi.org/10.1242/dev.02501
Published: 15 September 2006
View article titled, Transcriptional control of midbrain dopaminergic neuron development
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Journal Articles

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development

Stefan Glaser, Julia Schaft, Sandra Lubitz, Kristina Vintersten, Frank van der Hoeven, Katharina R. Tufteland, Rein Aasland, Konstantinos Anastassiadis, Siew-Lan Ang, A. Francis Stewart
Journal: Development
Development (2006) 133 (8): 1423–1432.
https://doi.org/10.1242/dev.02302
Published: 15 April 2006
View article titled, Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development
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Includes: Supplementary data
Journal Articles

Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons

Julianna Kele, Nicolas Simplicio, Anna L. M. Ferri, Helena Mira, François Guillemot, Ernest Arenas, Siew-Lan Ang
Journal: Development
Development (2006) 133 (3): 495–505.
https://doi.org/10.1242/dev.02223
Published: 1 February 2006
View article titled, Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
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Journal Articles

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

Eduardo Puelles, Alessandro Annino, Francesca Tuorto, Alessandro Usiello, Dario Acampora, Thomas Czerny, Claude Brodski, Siew-Lan Ang, Wolfgang Wurst, Antonio Simeone
Journal: Development
Development (2004) 131 (9): 2037–2048.
https://doi.org/10.1242/dev.01107
Published: 1 May 2004
View article titled, Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain
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Journal Articles

Foxa2 regulates alveolarization and goblet cell hyperplasia

Huajing Wan, Klaus H. Kaestner, Siew-Lan Ang, Machiko Ikegami, Fred D. Finkelman, Mildred T. Stahlman, Patricia C. Fulkerson, Marc E. Rothenberg, Jeffrey A. Whitsett
Journal: Development
Development (2004) 131 (4): 953–964.
https://doi.org/10.1242/dev.00966
Published: 15 February 2004
View article titled, Foxa2 regulates alveolarization and goblet cell hyperplasia
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Includes: Supplementary data
Journal Articles

Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo

Aitana Perea-Gomez, Kirstie A. Lawson, Muriel Rhinn, Lise Zakin, Philippe Brûlet, Sylvie Mazan, Siew-Lan Ang
Journal: Development
Development (2001) 128 (5): 753–765.
https://doi.org/10.1242/dev.128.5.753
Published: 1 March 2001
View article titled, Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo
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Journal Articles

HNF3 β and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo

Aitana Perea-Gómez, William Shawlot, Hiroshi Sasaki, Richard R. Behringer, Siew-Lan Ang
Journal: Development
Development (1999) 126 (20): 4499–4511.
https://doi.org/10.1242/dev.126.20.4499
Published: 15 October 1999
View article titled, HNF3 β and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo
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Journal Articles

Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain

Muriel Rhinn, Andrée Dierich, Marianne Le Meur, Siew-Lan Ang
Journal: Development
Development (1999) 126 (19): 4295–4304.
https://doi.org/10.1242/dev.126.19.4295
Published: 1 October 1999
View article titled, Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain
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Journal Articles

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification

Muriel Rhinn, Andrée Dierich, William Shawlot, Richard R. Behringer, Marianne Le Meur, Siew-Lan Ang
Journal: Development
Development (1998) 125 (5): 845–856.
https://doi.org/10.1242/dev.125.5.845
Published: 1 March 1998
View article titled, Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification
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Journal Articles

goosecoid and HNF-3 β genetically interact to regulate neural tube patterning during mouse embryogenesis

Stefania Filosa, Jaime A. Rivera-Pérez, Aitana Perea Gómez, Anne Gansmuller, Hitoshi Sasaki, Richard R. Behringer, Siew-Lan Ang
Journal: Development
Development (1997) 124 (14): 2843–2854.
https://doi.org/10.1242/dev.124.14.2843
Published: 15 July 1997
View article titled, goosecoid and HNF-3 β genetically interact to regulate neural tube patterning during mouse embryogenesis
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Journal Articles

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain

Siew-Lan Ang, Ou Jin, Muriel Rhinn, Nathalie Daigle, Lois Stevenson, Janet Rossant
Journal: Development
Development (1996) 122 (1): 243–252.
https://doi.org/10.1242/dev.122.1.243
Published: 1 January 1996
View article titled, A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain
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Journal Articles

Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants

Siew-Lan Ang, Ronald A. Conlon, Ou Jin, Janet Rossant
Journal: Development
Development (1994) 120 (10): 2979–2989.
https://doi.org/10.1242/dev.120.10.2979
Published: 1 October 1994
View article titled, Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants
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Journal Articles

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/ forkhead proteins

Siew-Lan Ang, Allison Wierda, David Wong, Kimberly A. Stevens, Stephanie Cascio, Janet Rossant, Kenneth S. Zaret
Journal: Development
Development (1993) 119 (4): 1301–1315.
https://doi.org/10.1242/dev.119.4.1301
Published: 1 December 1993
View article titled, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/ forkhead proteins
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Journal Articles

Anterior mesendoderm induces mouse Engrailed genes in explant cultures

Siew-Lan Ang, Janet Rossant
Journal: Development
Development (1993) 118 (1): 139–149.
https://doi.org/10.1242/dev.118.1.139
Published: 1 May 1993
View article titled, Anterior mesendoderm induces mouse Engrailed genes in explant cultures
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