Summary: This Review highlights the recent discoveries that govern gynoecium and fruit development in Arabidopsis and presents the currently known gene regulatory networks from gynoecium initiation until fruit maturation.
STEM CELLS AND REGENERATION
Highlighted Article: Transgenic overactivation of Notch signaling, which is required for bone regeneration following segmental mandibulectomy in zebrafish, accelerates bone healing through more efficient conversion of the cartilage callus to bone.
Newt Hoxa13 has an essential and predominant role in digit formation during development and regeneration
Highlighted Article: Knockout of newt Hox13 genes reveals that Hox13 function is conserved between limb development and regeneration, but that Hoxa13 has a predominant role in digit formation, unlike in mice.
Fatty acid-binding proteins and fatty acid synthase influence glial reactivity and promote the formation of Müller glia-derived progenitor cells in the chick retina
Summary: The activity of fatty acid binding proteins and fatty acid synthase are required for the formation of Müller glia-derived progenitors in the retina.
Olig2 defines a subset of neural stem cells that produce specific olfactory bulb interneuron subtypes in the subventricular zone of adult mice
Summary: Single cell transcriptomics and genetic studies reveal unique properties of Olig2-expressing neural stem cells in the adult subventricular zone and their developmental trajectory.
Summary: Two subtypes of astrocyte progenitor cells, marked by SPARC and SPARCL1, are distributed in discrete regions of the mouse forebrain at the start of gliogenesis.
High temperature perception in leaves promotes vascular regeneration and graft formation in distant tissues
Highlighted Article: This paper describes a pathway in which high temperatures are perceived by the leaves to promote an auxin-dependent signal that accelerates vascular regeneration, graft formation and plant parasitism in distant tissues.
The topography of corticopontine projections is controlled by postmitotic expression of the area-mapping gene Nr2f1
Summary: Cortical gradient expression of the area patterning gene Nr2f1 spatially and temporally controls corticopontine topographic connectivity in layer V projection neurons.
The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution
Highlighted Article: The gene regulatory network that controls segmentation in the wasp Nasonia is functionally similar to that of Drosophila, despite different modes of segmentation and 300 million years of divergence.
Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis
Summary: KIFC1 is important for microtubule acetylation-based spindle stability, and also plays a role in actin dynamics and spindle migration through Fmn2 and ARP2/3 function during mouse oocyte meiosis.
Warm and cold temperatures have distinct germline stem cell lineage effects during Drosophila oogenesis
Summary: Warm and cold temperatures reduce Drosophila egg production through distinct ovarian effects, providing insight into how the current climate crisis affects insect reproduction.
Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes
Summary: Polycomb repressor complex 2 inactivation results in selective effects on mouse hypothalamic development, increasing glutamatergic/GABA cells, while reducing dopamine, Hcrt and Tac2-Pax6 cells.
Summary: The H3.3 chaperone Hira complex has a maternal effect function in oocyte developmental competence and embryogenesis by modulating chromatin condensation and transcriptional quiescence.
TECHNIQUES AND RESOURCES
Summary: The stereotyped assembly of the zebrafish pectoral fin vasculature is documented from first migratory sprout into the limb bud, to the adult-like form of the 4-week-old larva.