Cover ImageCover: Composite image of a Drosophila wing imaginal disc demonstrating clonal expression of an activated mutant of Smoothened, the signal-transducing component of the Hedgehog pathway. Smoothened mutant expression (green) induces activation of downstream effectors and target genes (red and blue), triggering ectopic pathway activity and wing pouch duplication. See Research article by Carroll et al. on p. 612.Close Modal
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DEVELOPMENT AT A GLANCE
DEVELOPMENT AND STEM CELLS
Cdx2 determines the fate of postnatal intestinal endoderm
p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
LACHESIS-dependent egg-cell signaling regulates the development of female gametophytic cells
Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells
Wnt/β-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer’s vesicle
Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways
αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly
CycA is involved in the control of endoreplication dynamics in the Drosophila bristle lineage
Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila
DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress
The genomic regulatory control of skeletal morphogenesis in the sea urchin
Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons
Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh
The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis
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