Cover ImageCover: False-colored scanning electron micrograph of an outer whorl organ from an apetala2-2 mutant flower. In the absence of APETALA2-mediated repression, floral organ identity genes are misregulated, resulting in the depicted sepal-to-carpel homeotic conversion. The specimen is shown in abaxial (or ventral) view. See Research article by Krogan et al. on p. 4180.
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DEVELOPMENT AT A GLANCE
DEVELOPMENT AND STEM CELLS
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development
Migration of cardiomyocytes is essential for heart regeneration in zebrafish
Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis
Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen
Wapl antagonizes cohesin binding and promotes Polycomb-group silencing in Drosophila
APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19
Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans
Cytoplasmic Ca2+ changes dynamically during the interaction of the pollen tube with synergid cells
Age-related changes in expression and function of Toll-like receptors in human skin
BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border
Gata2 provides an early anterior bias and uncovers a global positioning system for polarity in the amniote embryo
Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme
Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds
The roof plate boundary is a bi-directional organiser of dorsal neural tube and choroid plexus development
Quantitative semi-automated analysis of morphogenesis with single-cell resolution in complex embryos
Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM JOURNAL OF CELL SCIENCE
Impact of substrate elasticity on human hematopoietic stem and progenitor cell adhesion and motility
The PDZ-GEF protein Dizzy regulates the establishment of adherens junctions required for ventral furrow formation in Drosophila
IN THIS ISSUE
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