Cover ImageCover: A flat-mounted retina from an E16.5 mouse embryo electroporated in utero with a Ptc1?loop2 construct and EGFP reporter (green), showing retinal ganglion cells where Shh signal transduction has been abrogated. The retina is counterstained with Hoechst (blue). Shh secreted from retinal ganglion cells is autonomously required for the proper growth and navigation of retinal axons. See research article by Sánchez-Camacho and Bovolenta on p. 3531.
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The endosperm-specific ZHOUPI gene of Arabidopsis thaliana regulates endosperm breakdown and embryonic epidermal development
Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2
PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression
Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons
Functional resolution of duplicated hoxb5 genes in teleosts
DEVELOPMENT AND DISEASE
Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract
PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1α signaling and endoplasmic reticulum stress
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart
Frs2α-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis
Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM JOURNAL OF CELL SCIENCE
Snail is required for TGFβ-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells
αII-βV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells
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