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Volume 135, Issue 12

June 2008

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Cover image

Cover Image

Cover: Ventral view of the head of a 4-day-old zebrafish embryo showing that slow twitch muscle fibres, labelled with the pan-slow myosin antibody S58 (red), differentially express a smyhc1:gfp reporter gene (green) and the smyhc2 gene (blue), reflecting a molecular diversity within specific muscle fibre types. See research article by Elworthy et al. on p. 2115.
Table of contents

ISSN 0950-1991

EISSN 1477-9129

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IN THIS ISSUE

REVIEW

Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture

Markus Affolter,Emmanuel Caussinus

Abstract

View articletitled, Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture

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RESEARCH REPORT

Cell cycle progression is required for zebrafish somite morphogenesis but not segmentation clock function

Lixia Zhang,Christina Kendrick,Dörthe Jülich,Scott A. Holley

Abstract

View articletitled, Cell cycle progression is required for zebrafish somite morphogenesis but not segmentation clock function

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RESEARCH ARTICLE

Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment

Felix Lohmann,James J. Bieker

Abstract

View articletitled, Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment

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Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

David G. Simmons,David R. C. Natale,Valerie Begay,Martha Hughes,Achim Leutz,James C. Cross

Abstract

View articletitled, Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

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Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling

Sandra Blaess,Daniel Stephen,Alexandra L. Joyner

Abstract

View articletitled, Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling

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A maternally localised Wnt ligand required for axial patterning in the cnidarian Clytia hemisphaerica

Tsuyoshi Momose,Romain Derelle,Evelyn Houliston

Abstract

View articletitled, A maternally localised Wnt ligand required for axial patterning in the cnidarian Clytia hemisphaerica

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Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity

Stone Elworthy,Murray Hargrave,Robert Knight,Katharina Mebus,Philip W. Ingham

Abstract

View articletitled, Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity

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Selective expression of Kras^G12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

Heng-Yu Fan,Masayuki Shimada,Zhilin Liu,Nicola Cahill,Noritaka Noma,Yun Wu,Jan Gossen,JoAnne S. Richards

Abstract

View articletitled, Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

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C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment

Anne K. Voss,Joanne M. Britto,Mathew P. Dixon,Bilal N. Sheikh,Caitlin Collin,Seong-Seng Tan,Tim Thomas

Abstract

View articletitled, C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment

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Signals from the neural crest regulate beta-cell mass in the pancreas

Nada Nekrep,Juehu Wang,Takeshi Miyatsuka,Michael S. German

Abstract

View articletitled, Signals from the neural crest regulate beta-cell mass in the pancreas

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Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

Yuhang Zhang,Thomas Andl,Steven H. Yang,Monica Teta,Fei Liu,John T. Seykora,John W. Tobias,Stefano Piccolo,Ruth Schmidt-Ullrich,Andras Nagy,Makoto M. Taketo,Andrzej A. Dlugosz,Sarah E. Millar

Abstract

View articletitled, Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

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Ca²⁺ signals coordinate zygotic polarization and cell cycle progression in the brown alga Fucus serratus

John H. F. Bothwell,Jolanta Kisielewska,Martin J. Genner,Martin R. McAinsh,Colin Brownlee

Abstract

View articletitled, Ca2+ signals coordinate zygotic polarization and cell cycle progression in the brown alga Fucus serratus

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Multiple modular promoter elements drive graded brinkerexpression in response to the Dpp morphogen gradient

Li-Chin Yao,Sopheap Phin,Jane Cho,Christine Rushlow,Kavita Arora,Rahul Warrior

Abstract

View articletitled, Multiple modular promoter elements drive graded brinkerexpression in response to the Dpp morphogen gradient

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Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

Timothy R. Carlson,Huiqing Hu,Rickmer Braren,Yung Hae Kim,Rong A. Wang

Abstract

View articletitled, Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

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FROM JOURNAL OF CELL SCIENCE

Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis

Tohru Matsuki,Albéna Pramatarova,Brian W. Howell

View articletitled, Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis

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The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors

Bryan L. Krock,Brian D. Perkins

View articletitled, The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors

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IN THIS ISSUE

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Accepted manuscripts

Chemokine-like Orion is involved in the transformation of glial cells into phagocytes in different developmental neuronal remodeling paradigms

Clarisse Perron, Pascal Carme, Arnau Llobet Rosell, Eva Minnaert, Salomé Ruiz Demoulin, Héloïse Szczkowski, Lukas Jakob Neukomm, Jean-Maurice Dura, Ana Boulanger

The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs

Shou Soeda, Masaaki Oyama, Hiroko Kozuka-Hata, Tadashi Yamamoto

The Tbx20-TLE interaction is essential for the maintenance of the second heart field

Whitney Edwards, Olivia K. Bussey, Frank L. Conlon

scTOP: physics-inspired order parameters for cellular identification and visualization

Maria Yampolskaya, Michael J. Herriges, Laertis Ikonomou, Darrell N. Kotton, Pankaj Mehta

Meningeal origins and dynamics of perivascular fibroblast development on the mouse cerebral vasculature

Hannah E. Jones, Vanessa Coelho-Santos, Stephanie K. Bonney, Kelsey A. Abrams, Andy Y. Shih, Julie A. Siegenthaler

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Development presents... live stream of our Journal Meeting

Development presents advert outlining details of the live stream.

Watch a session from Development’s Journal Meeting, Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology which was live on the Node Monday 18 September.

Navigating a research career with a disability

Images showing resources which can aid disabled researchers in the lab. Red Dycem tape enhances the grip of objects, such as this 500 ml bottle, making it easier to open bottles and lift heavier objects, and provides stability for fine motor tasks. The height-adjustable black armrest provides support at the lab bench. It can be used to provide stability during fine motor tasks (such as dissections) or decrease fatigue from repetitive tasks, such as pipetting.

Our two recent Perspectives articles explore the lived experiences of disabled scientists in our community. Kelsey L. Anbuhl and colleagues describe the lived experiences of five biologists who share the challenges and successes of undertaking a scientific career with a disability. Whereas Jack Darius Morgan reviews the literature exploring disabled scientists’ experiences in academia.

Focus on regeneration

Transverse sections of ventricles isolated from fish in the experiment illustrated in B, fluorescently stained for pS6 and F-actin. The areas that are shown at higher magnification are outlined. n≥5.

Tissue regeneration is a fascinating phenomenon, but the cellular and molecular mechanisms underlying regeneration remain incompletely understood. Here, Development has collated a series of articles showcasing some of the most recent advances in regenerative biology.

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Keep up with the Node 'Lab meeting' posts as the platform regularly highlights development and stem cell biology labs from across the globe and showcases research and researchers from the community. August featured the Nichols lab at the University of Edinburgh, read their 'Lab meeting' article here.

Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.

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