Cover ImageCover: An embryonic mouse salivary epithelium cultured in laminin-111 with FGF10 (a sub-optimal dose for growth) and recombinant, active heparanase. The heparanase cleaves heparan sulfate and increases FGF10 bioactivity resulting in increased lateral branching, end-bud clefting and duct elongation. See research article by Patel et al. on p. 4177.
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Delamination of cells from neurogenic placodes does not involve an epithelial-to-mesenchymal transition
Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo
Functional analyses of genetic pathways controlling petal specification in poppy
Synaptic differentiation is defective in mice lacking acetylcholine receptor β-subunit tyrosine phosphorylation
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction
PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary
Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus
Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis
Senseless functions as a molecular switch for color photoreceptor differentiation in Drosophila
Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling
Argonaute 1 regulates the fate of germline stem cells in Drosophila
A wave of EGFR signaling determines cell alignment and intercalation in the Drosophila tracheal placode
Granulosa cells regulate oocyte intracellular pH against acidosis in preantral follicles by multiple mechanisms
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Mitochondrial DNA replication during differentiation of murine embryonic stem cells
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