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Volume 134, Issue 16

August 2007

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Cover Image

Cover: The skeleton of a mouse embryo at E18.5. Loss of Hox9 paralogous function causes dramatic defects in rib cage development. Thirteen thoracic ribs attach to the sternum instead of the normal seven, along with four extra vertebrae with unattached ribs. Hox5, Hox6 and Hox9 paralogous mutants all show dramatic defects in axial patterning. See research article by McIntyre et al. on p. 2981 .
Table of contents

ISSN 0950-1991

EISSN 1477-9129

In this issue

RESEARCH REPORT
RESEARCH ARTICLE
DEVELOPMENT AND DISEASE
IN THIS ISSUE

RESEARCH REPORT

A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification

Marios P. Stavridis,J. Simon Lunn,Barry J. Collins,Kate G. Storey

Abstract

View articletitled, A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification

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FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment

Tilo Kunath,Marc K. Saba-El-Leil,Marwa Almousailleakh,Jason Wray,Sylvain Meloche,Austin Smith

Abstract

View articletitled, FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment

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RESEARCH ARTICLE

Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia

Victor L. Ruiz-Perez,Helen J. Blair,M. Elena Rodriguez-Andres,Maria Jose Blanco,Amy Wilson,Yu-Ning Liu,Colin Miles,Heiko Peters,Judith A. Goodship

Abstract

View articletitled, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia

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EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

Maike Schmidt,Kim Paes,Ann De Mazière,Tanya Smyczek,Stacey Yang,Alane Gray,Dorothy French,Ian Kasman,Judith Klumperman,Dennis S. Rice,Weilan Ye

Abstract

View articletitled, EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

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Spatiotemporal definition of neurite outgrowth, refinement and retraction in the developing mouse cochlea

Lin-Chien Huang,Peter R. Thorne,Gary D. Housley,Johanna M. Montgomery

Abstract

View articletitled, Spatiotemporal definition of neurite outgrowth, refinement and retraction in the developing mouse cochlea

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Semaphorin signaling facilitates cleft formation in the developing salivary gland

Ling Chung,Tsung-Lin Yang,Hsiu-Ru Huang,Su-Ming Hsu,Hwai-Jong Cheng,Pei-Hsin Huang

Abstract

View articletitled, Semaphorin signaling facilitates cleft formation in the developing salivary gland

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The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

Anas Fadloun,Dominique Kobi,Jean-Christophe Pointud,Arup Kumar Indra,Marius Teletin,Christine Bole-Feysot,Barbara Testoni,Roberto Mantovani,Daniel Metzger,Gabrielle Mengus,Irwin Davidson

Abstract

View articletitled, The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

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Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY

Kyoko Ohashi-Ito,Dominique C. Bergmann

Abstract

View articletitled, Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY

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Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction

Felicia Chen,Tushar J. Desai,Jun Qian,Karen Niederreither,Jining Lü,Wellington V. Cardoso

Abstract

View articletitled, Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction

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Hox patterning of the vertebrate rib cage

Daniel C. McIntyre,Sabita Rakshit,Alisha R. Yallowitz,Luke Loken,Lucie Jeannotte,Mario R. Capecchi,Deneen M. Wellik

Abstract

View articletitled, Hox patterning of the vertebrate rib cage

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Two C. elegans histone methyltransferases repress lin-3EGF transcription to inhibit vulval development

Erik C. Andersen,H. Robert Horvitz

Abstract

View articletitled, Two C. elegans histone methyltransferases repress lin-3EGF transcription to inhibit vulval development

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Recruitment of cells into the Drosophila wing primordium by a feed-forward circuit of vestigial autoregulation

Myriam Zecca,Gary Struhl

Abstract

View articletitled, Recruitment of cells into the Drosophila wing primordium by a feed-forward circuit of vestigial autoregulation

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Control of Drosophila wing growth by the vestigialquadrant enhancer

Myriam Zecca,Gary Struhl

Abstract

View articletitled, Control of Drosophila wing growth by the vestigialquadrant enhancer

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DEVELOPMENT AND DISEASE

Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea

Bonnie E. Jacques,Mireille E. Montcouquiol,Erynn M. Layman,Mark Lewandoski,Matthew W. Kelley

Abstract

View articletitled, Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea

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Dual role of Mpl receptor during the establishment of definitive hematopoiesis

Laurence Petit-Cocault,Cécile Volle-Challier,Maud Fleury,Bruno Péault,Michèle Souyri

Abstract

View articletitled, Dual role of Mpl receptor during the establishment of definitive hematopoiesis

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Endoglin is required for hemangioblast and early hematopoietic development

Rita C. R. Perlingeiro

Abstract

View articletitled, Endoglin is required for hemangioblast and early hematopoietic development

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IN THIS ISSUE

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Accepted manuscripts alert

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Latest published articles alert

Accepted manuscripts

The mouse Pramel1 regulates spermatogonial development by inhibiting the retinoic acid (RA) signaling during spermatogenesis

Mingyao Yang, Wenzhi Ma, Jon Oatley, Wan-Sheng Liu

The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs

Shou Soeda, Masaaki Oyama, Hiroko Kozuka-Hata, Tadashi Yamamoto

The Tbx20-TLE interaction is essential for the maintenance of the second heart field

Whitney Edwards, Olivia K. Bussey, Frank L. Conlon

A CDC-42-regulated actin network contributes to nuclear migration through constricted spaces in C. elegans

Jamie Ho, Leslie A. Guerrero, Diana Libuda, G. W. Gant Luxton, Daniel A. Starr

The Foxi3 transcription factor is necessary for the fate restriction of placodal lineages at the neural plate border

Ankita Thawani, Helen R. Maunsell, Hongyuan Zhang, Harinarayana Ankamreddy, Andrew K. Groves

More accepted manuscripts

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Development presents... live stream of our Journal Meeting

Development presents advert outlining details of the live stream.

Watch a session from Development’s Journal Meeting, Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology which was live on the Node Monday 18 September.

Navigating a research career with a disability

Images showing resources which can aid disabled researchers in the lab. Red Dycem tape enhances the grip of objects, such as this 500 ml bottle, making it easier to open bottles and lift heavier objects, and provides stability for fine motor tasks. The height-adjustable black armrest provides support at the lab bench. It can be used to provide stability during fine motor tasks (such as dissections) or decrease fatigue from repetitive tasks, such as pipetting.

Our two recent Perspectives articles explore the lived experiences of disabled scientists in our community. Kelsey L. Anbuhl and colleagues describe the lived experiences of five biologists who share the challenges and successes of undertaking a scientific career with a disability. Whereas Jack Darius Morgan reviews the literature exploring disabled scientists’ experiences in academia.

Focus on regeneration

Transverse sections of ventricles isolated from fish in the experiment illustrated in B, fluorescently stained for pS6 and F-actin. The areas that are shown at higher magnification are outlined. n≥5.

Tissue regeneration is a fascinating phenomenon, but the cellular and molecular mechanisms underlying regeneration remain incompletely understood. Here, Development has collated a series of articles showcasing some of the most recent advances in regenerative biology.

Keeping up with the Node: Lab meetings

Keep up with the Node 'Lab meeting' posts as the platform regularly highlights development and stem cell biology labs from across the globe and showcases research and researchers from the community. August featured the Nichols lab at the University of Edinburgh, read their 'Lab meeting' article here.

Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.

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