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Volume 134, Issue 14

July 2007

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Cover Image

Cover: Understanding the developmental signals that enable cells to build complex tissue and organ structures may lead to major advances in regenerative medicine. Here, two ectopic limbs have been induced in Xenopus laevis by modulating expression of K⁺ channels and thereby altering bioelectrical signaling in the early embryo (image courtesy of Sherry Aw). See meeting review by Ingber and Levin on p. 2541.
Table of contents

ISSN 0950-1991

EISSN 1477-9129

In this issue

MEETING REVIEW
REVIEW
RESEARCH REPORT
RESEARCH ARTICLE
IN THIS ISSUE

MEETING REVIEW

What lies at the interface of regenerative medicine and developmental biology?

Donald E. Ingber,Michael Levin

Abstract

View articletitled, What lies at the interface of regenerative medicine and developmental biology?

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REVIEW

The rise and fall of Hox gene clusters

Denis Duboule

Abstract

View articletitled, The rise and fall of Hox gene clusters

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RESEARCH REPORT

AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis

Danielle P. Vidaurre,Sara Ploense,Naden T. Krogan,Thomas Berleth

Abstract

View articletitled, AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis

Supplementary information

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RESEARCH ARTICLE

Ftm is a novel basal body protein of cilia involved in Shh signalling

Jeanette Vierkotten,Renate Dildrop,Thomas Peters,Baolin Wang,Ulrich Rüther

Abstract

View articletitled, Ftm is a novel basal body protein of cilia involved in Shh signalling

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Involvement of vessels and PDGFB in muscle splitting during chick limb development

Samuel Tozer,Marie-Ange Bonnin,Frédéric Relaix,Sandrine Di Savino,Pilar García-Villalba,Pascal Coumailleau,Delphine Duprez

Abstract

View articletitled, Involvement of vessels and PDGFB in muscle splitting during chick limb development

Supplementary information

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Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells

Koji Sugiura,You-Qiang Su,Francisco J. Diaz,Stephanie A. Pangas,Shweta Sharma,Karen Wigglesworth,Marilyn J. O'Brien,Martin M. Matzuk,Shunichi Shimasaki,John J. Eppig

Abstract

View articletitled, Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells

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A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense

Theodore Tsichritzis,Peer C. Gaentzsch,Stylianos Kosmidis,Anthony E. Brown,Efthimios M. Skoulakis,Petros Ligoxygakis,George Mosialos

Abstract

View articletitled, A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense

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Defective osteoblast function in ICAP-1-deficient mice

Daniel Bouvard,Attila Aszodi,Günter Kostka,Marc R. Block,Corinne Albigès-Rizo,Reinhard Fässler

Abstract

View articletitled, Defective osteoblast function in ICAP-1-deficient mice

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Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice

Yoshiyuki Seki,Masashi Yamaji,Yukihiro Yabuta,Mitsue Sano,Mayo Shigeta,Yasuhisa Matsui,Yumiko Saga,Makoto Tachibana,Yoichi Shinkai,Mitinori Saitou

Abstract

View articletitled, Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice

Supplementary information

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Cohesin-dependent regulation of Runx genes

Julia A. Horsfield,Sasha H. Anagnostou,Jimmy Kuang-Hsien Hu,Kitty Hsiao Yu Cho,Robert Geisler,Graham Lieschke,Kathryn E. Crosier,Philip S. Crosier

Abstract

View articletitled, Cohesin-dependent regulation of Runx genes

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G-protein-coupled signals control cortical actin assembly by controlling cadherin expression in the early Xenopus embryo

Qinghua Tao,Sumeda Nandadasa,Pierre D. McCrea,Janet Heasman,Christopher Wylie

Abstract

View articletitled, G-protein-coupled signals control cortical actin assembly by controlling cadherin expression in the early Xenopus embryo

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Common regulatory networks in leaf and fruit patterning revealed by mutations in the Arabidopsis ASYMMETRIC LEAVES1 gene

Hugo Alonso-Cantabrana,Juan José Ripoll,Isabel Ochando,Antonio Vera,Cristina Ferrándiz,Antonio Martínez-Laborda

Abstract

View articletitled, Common regulatory networks in leaf and fruit patterning revealed by mutations in the Arabidopsis ASYMMETRIC LEAVES1 gene

Supplementary information

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Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency

Frank M. J. Jacobs,Simone M. Smits,Cornelle W. Noorlander,Lars von Oerthel,Annemarie J. A. van der Linden,J. Peter H. Burbach,Marten P. Smidt

Abstract

View articletitled, Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency

Supplementary information

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Binary cell fate specification during C. elegans embryogenesis driven by reiterated reciprocal asymmetry of TCF POP-1 and its coactivatorβ-catenin SYS-1

Shuyi Huang,Premnath Shetty,Scott M. Robertson,Rueyling Lin

Abstract

View articletitled, Binary cell fate specification during C. elegans embryogenesis driven by reiterated reciprocal asymmetry of TCF POP-1 and its coactivatorβ-catenin SYS-1

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Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons

Nicholas D. Murchison,Brian A. Price,David A. Conner,Douglas R. Keene,Eric N. Olson,Clifford J. Tabin,Ronen Schweitzer

Abstract

View articletitled, Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons

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IN THIS ISSUE

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Accepted manuscripts alert

Table of contents alert

Latest published articles alert

Accepted manuscripts

PAR-4/LKB1 prevents intestinal hyperplasia by restricting endoderm specification in C. elegans embryos

Flora Demouchy, Ophélie Nicolle, Grégoire Michaux, Anne Pacquelet

Energy metabolism modulates the regulatory impact of activators on gene expression

Sha Qiao, Sebastian Bernasek, Kevin D. Gallagher, Jessica O'Connell, Shigehiro Yamada, Neda Bagheri, Luis A. N. Amaral, Richard W. Carthew

BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation

Rachel E. Musa, Kaitlyn L. Lester, Gabrielle A. Quickstad, Sara Vardabasso, Trevor V. Shumate, Ryan T. Salcido, Kai Ge, Karl B. Shpargel

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway

Timothy T. Nguyen, Jennyfer M. Mitchell, Michaela D. Kiel, Colin P. Kenny, Hong Li, Kenneth L. Jones, Robert A. Cornell, Trevor J. Williams, James T. Nichols, Eric Van Otterloo

Excess dietary sugar impairs Drosophila adult stem cells via elevated ROS-JNK signaling

Wei-Hao Huang, Kreeti Kajal, Ryan Himawan Wibowo, Oyundari Amartuvshin, Shih-Han Kao, Elham Rastegari, Chi-Hung Lin, Kuan-Lin Chiou, Hai-Wei Pi, Chau-Ti Ting, Hweijan Hsu

More accepted manuscripts

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Development presents... live stream of our Journal Meeting

Development presents advert outlining details of the live stream.

Watch a session from Development’s Journal Meeting, Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology which was live on the Node Monday 18 September.

Navigating a research career with a disability

Images showing resources which can aid disabled researchers in the lab. Red Dycem tape enhances the grip of objects, such as this 500 ml bottle, making it easier to open bottles and lift heavier objects, and provides stability for fine motor tasks. The height-adjustable black armrest provides support at the lab bench. It can be used to provide stability during fine motor tasks (such as dissections) or decrease fatigue from repetitive tasks, such as pipetting.

Our two recent Perspectives articles explore the lived experiences of disabled scientists in our community. Kelsey L. Anbuhl and colleagues describe the lived experiences of five biologists who share the challenges and successes of undertaking a scientific career with a disability. Whereas Jack Darius Morgan reviews the literature exploring disabled scientists’ experiences in academia.

Focus on regeneration

Transverse sections of ventricles isolated from fish in the experiment illustrated in B, fluorescently stained for pS6 and F-actin. The areas that are shown at higher magnification are outlined. n≥5.

Tissue regeneration is a fascinating phenomenon, but the cellular and molecular mechanisms underlying regeneration remain incompletely understood. Here, Development has collated a series of articles showcasing some of the most recent advances in regenerative biology.

Keeping up with the Node: Lab meetings

Keep up with the Node 'Lab meeting' posts as the platform regularly highlights development and stem cell biology labs from across the globe and showcases research and researchers from the community. September featured the Kerosuo lab at the National Institute of Dental and Craniofacial Research, read their 'Lab meeting' article here.

Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.

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