Reconstructing the transcriptional ontogeny of maize and sorghum supports an inverse hourglass model of inflorescence development by Leiboff & Hake
Evolving a body plan: Transcriptional ontogeny of maize and sorghum supports an inverse hourglass model for inflorescence development.
Selected by Alexa Sadier. Read the preLight here
Resolving the 3D landscape of transcription-linked mammalian chromatin folding by Hsieh et al.
When smaller is better – Micro-C reveals transcription-linked chromatin architecture at very high resolution.
Selected by Clarice Hong. Read the preLight here
Species-specific oscillation periods of human and mouse segmentation clocks are due to cell autonomous differences in biochemical reaction parameters by Matsuda et al.
The time is now: understanding developmental timescales by inter-species comparison of the oscillation period in the presomitic mesoderm.
Selected by Teresa Rayon. Read the preLight here
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Computational Modelling in the era of quantitative developmental biology
Selected by Irepan Salvador Martinez. Read the preLight here
A conserved regulatory program drives emergence of the lateral plate mesoderm by Prummel et al.
Identification of a lateral plate mesoderm enhancer with evolutionarily conserved function.
Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects by Mereu et al.
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Systematic comparative analysis of single cell RNA-sequencing methods by Ding et al.
RNAseq is now a practical, high-throughput and economically viable approach to determine cell fate and state at single cell resolution. As consortia form to generate tissue/organ ‘atlases’, these preprints compare RNA sequencing techniques.
High-throughput mapping of mesoscale connectomes in individual mice by Huang et al.
Behavior can vary widely among individuals. A recent study developed a commanding technique to reconstruct whole-cortex connectomes using a single animal, with ensuing applications for measuring individual variability in neuronal wiring.
Selected by Dena Goldblatt. Read the preLight here
OptiJ: Open-source optical projection tomography of large organ samples by Ramirez et al.
A tool for all- OptiJ: an easy-to-assemble setup and freely available software as an incentive for widescale implementation of OPT.
Selected by Mariana De Niz. Read the preLight here
Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics by Clement et al.
Adipocytes donate packets of energy to melanoma cells to stimulate their mitochondrial metabolism and fuel cell motility.
Selected by Hannah Brunsdon.Read the preLight here
Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits by Roth et al.
T-cells for everyone! A platform to screen functionality of novel DNA sequences in T-cells.
Selected by Pavithran Ravindran. Read the preLight here
Integrated Metabolomic and Transcriptomic Profiling Reveals Novel Activation-Induced Metabolic Networks in Human T cells by Hiemer et al.
Feeding immunity: TCR stimulation leads to metabolic rewiring in human T cells to promote glucose and amino acid metabolism.
Selected by Jonny Coates. Read the preLight here
