Trichomes - branched hair-like cells on the surface of plants - have a highly organised actin filament cytoskeleton, and their development provides an interesting model for understanding how plants generate and use cytoskeletal arrays. The `distorted group' genes have been particularly valuable in this regard (so called because they distort trichome shape), and on p. 4345, Basu and co-workers characterise the Arabidopsis distorted gene PIROGI. They find that PIROGI has 30% homology with SRA1 - a subunit of the human WAVE complex - that, together with actin-related protein 2/3,controls actin filament nucleation. Remarkably, SRA1 cDNA is able to rescue the phenotype of PIROGI mutants, and both proteins interact with another component of the Arabidopsis WAVE complex, NAP125. Their findings indicate that PIROGI itself encodes a WAVE subunit, and underline the importance of the distorted group genes in our understanding of actin filament regulation, cell shape and growth.
Breaking the WAVE
Breaking the WAVE. Development 1 September 2004; 131 (17): e1704. doi:
Download citation file:
Advertisement
Cited by
Call for papers: Uncovering Developmental Diversity
Development invites you to submit your latest research to our upcoming special issue: Uncovering Developmental Diversity. This issue will be coordinated by our academic Editor Cassandra Extavour (Harvard University, USA) alongside two Guest Editors: Liam Dolan (Gregor Mendel Institute of Molecular Plant Biology, Austria) and Karen Sears (University of California Los Angeles, USA).
Choose Development in 2024
In this Editorial, Development Editor-in-Chief James Briscoe and Executive Editor Katherine Brown explain how you support your community by publishing in Development and how the journal champions serious science, community connections and progressive publishing.
Journal Meeting: From Stem Cells to Human Development
Register now for the 2024 Development Journal Meeting From Stem Cells to Human Development. Early-bird registration deadline: 3 May. Abstract submission deadline: 21 June.
Pluripotency of a founding field: rebranding developmental biology
This collaborative Perspective, the result of a workshop held in 2023, proposes a set of community actions to increase the visibility of the developmental biology field. The authors make recommendations for new funding streams, frameworks for collaborations and mechanisms by which members of the community can promote themselves and their research.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.