... Attribution License ( http://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. 3D culture Cilia Goblet cell Human nasal epithelial cells Nasal organoid Characterization...

...Roberta Azzarelli; Michela Ori; Anna Philpott; Benjamin D. Simons ABSTRACT Emerging three-dimensional (3D) cultures of glioblastoma are becoming powerful models to study glioblastoma stem cell behavior and the impact of cell–cell and cell–microenvironment interactions on tumor growth and invasion...

... proliferation, but not invasion or changes in E-cadherin or TWIST1 expression in 3D cultures ( Fig. 6 B–D, Figs S6 and S7A,B ). These data indicate an association between the level of ALDH1A1 knockdown to effects on cell proliferation in CCR2-overexpressing SUM225 cells. We examined the role of ALDH1A1...