The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting
Summary: We describe recent advances and new directions in extracellular matrix research presented at the 2021 hybrid scientific meeting organized by the American Society for Matrix Biology.
Summary: The Drosophila genes rumpel, bumpel and kumpel, that encode SLC5A proteins expressed in overlapping sets of CNS glial cells act in partially redundant manner during locomotor control and oogenesis.
METHODS & TECHNIQUES
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing
Summary: Early developmental abnormalities in myotonic dystrophy type 1 are reiterated in vitro in myotubes differentiated from human embryonic stem cells that carry the mutation.